Albendazole - anti-protozoan and anthelminthic medicament from group of benzimidazole to a carbamate. Drug affects both intestinal, and tissue parasites in the form of eggs, larvae and adult helminths. Anthelminthic effect of albendazole is caused by oppression of polymerization of a tubulin that leads to disturbance of metabolism and death of helminths.

Albendazole destroys cysts or considerably reduces their sizes (to 80%) at patients with granular echinococcosis. After treatment by albendazole the quantity of impractical cysts increases to 90% in comparison with 10% at the patients who were not receiving medical treatment. After use of albendazole for treatment of the cysts caused by Echinococcus multilocularis, the absolute recovery was observed at a smaller part of patients, at the majority - improvement or stabilization of a state.

Indications

Intestinal forms of helminthoses and skin syndrome of Larva Migrans (short-term treatment by small doses): an enterobiosis, a dochmiasis and a necatoriasis, a hymenolepiasis, a teniosis, a strongyloidosis, an ascaridosis, a trichuriasis, a clonorchosis, an opisthorchosis, a skin syndrome of Larva Migrans, a giardiasis at children.

System helminthic infections (long-term treatment by high doses):

cystic echinococcosis (caused by Echinococcus granulosus):

• at impossibility of surgical intervention
• before surgical intervention
• after operation if preoperative treatment was short if distribution of helminths is observed or during operation found live forms;
• after carrying out a transdermal drainage of cysts with the diagnostic or therapeutic purpose;

alveolar echinococcosis (caused by Echinococcus multilocularis):

• at inoperable a disease, in particular in cases of the local or remote metastases;
• after palliative surgical intervention
• after radical surgical intervention or liver transplantation

neurocysticercosis (Taenia solium caused by larvae):

• in the presence of single or multiple cysts or at granulematozny damage of a brain
• at arachnoidal or intra ventricular cysts;
• at racemose cysts;

kapillyaroz (the caused Capillaria philippinensis), a gnatostomoza (the caused Gnathostoma spinigerum and sibling species), the trichinosis (caused by Trichinella spiralis and T.pseudospiralis), toksokaroz (the caused Toxocara canis and sibling species).

Contraindication

Hypersensitivity to albendazole or to any component of drug.

Period of pregnancy and feeding by a breast.

to the Women planning pregnancy. Women of reproductive age should apply effective non-hormonal contraceptive remedies in time and within 1 month after treatment.

Use during pregnancy or feeding by a breast

Drug is contraindicated to

for use during pregnancy and feeding by a breast and for treatment of the women planning pregnancy.

to

Children

Drug is contraindicated to children aged till 1 year.

Ability to influence speed of response at control of motor transport or other mechanisms.

Considering existence of such side reaction as dizziness, it is recommended to abstain for use of albendazole from control of motor transport and work with mechanisms.

Route of administration and doses

Intestinal forms and a skin syndrome of Larva Migrans

to take the Drug together with food. Before use to shake up. It is desirable to apply at the same time day. If there does not occur recovery in 3 weeks, the doctor has to appoint the second year of treatment.

At body weight less than 60 kg at the rate of 15 mg/kg/days. This dose should be divided into 2 receptions. The maximum daily dose - 800 mg.

Overdose

in case of overdose the symptomatic treatment, agrees a clinical state.

Structure

active ingredient: albendazole;

10 ml of suspension;

Excipients: aluminum-magnesium silicate, sodium carboxymethylcellulose, glycerin, polysorbate 80, sorbitanlaurate, potassium sorbate, benzoic acid, sorbic acid, anti-foam silicone 1510, sodium saccharin, fragrance orange, fragrance vanilla, fragrance intensively fruit, the water purified.

to Store

at a temperature below 25 °C. To store out of children's reach. To protect from impact of direct sunlight. To shake up before use.

Expiration date - 3 years.