Wangkowang – antimicrobial means for system use, for treatment of the infections caused by the gram-positive microorganisms sensitive to medicine including at patients with an allergy to penicillin and cephalosporins in the anamnesis:

• endocarditis;
• sepsis;
• osteomyelitis;
• an infection of the central nervous system;
• an infection of lower parts of airways (pneumonia);
• an infection of skin and soft tissues;
• pseudomembranous colitis (for use inside).

Structure

• active ingredient: vancomycin;
• 1 bottle contains Vancomycinum hydrochloride in transfer to Vancomycinum 1000 mg;
• other components: sodium hydroxide, Acidum hydrochloricum.

Contraindication

Hypersensitivity to Vancomycinum or to any other component of medicine.

Route of administration

Intravenous use

to Dissolve bottle contents on 500 mg in 10 ml or contents of a bottle on 1 g in 20 ml of water for injections.

After dilution stable within 24 hours at a temperature of 25 °C or within 96 hours in the fridge at a temperature from 2 to 8 °C. Further cultivation is necessary: it is necessary to add at least 100 ml or 200 ml of 0.9% of solution of sodium of chloride for injections to the solution containing 500 mg or 1 g of Vancomycinum or 5% of solution of glucose for injections respectively. The received solution remains stable during 48 h in the fridge at a temperature from 2 to 8 With or during 24 h at a temperature of 25 °C.

Feature of use

Fast administration of medicine in the form of a bolyusny injection (within several minutes) can cause considerable arterial hypotension, including shock, occasionally with cardiac arrest therefore for reduction of risk of development of hypotensive reactions it is necessary to control arterial blood pressure of the patient at administration of medicine.

Use of Vancomycinum in the I trimester of pregnancy is contraindicated to

. Prescribing of Vancomycinum in ІІ and ІІІ trimesters of pregnancy is possible only according to vital indications when the expected advantage for mother exceeds risk for a fruit, at the same time it is necessary to control concentration of Vancomycinum in blood serum.

Children

Medicine can be applied by

to children right after the birth.

Drivers

during use of medicine the ability to concentrate attention that should be considered when driving or performing the work requiring the enhanced attention can decrease.

Overdose

Symptoms.

Overdose is characterized by strengthening of expressiveness of by-effects.

Side effects

from a cardiovascular system: heart failure, arterial hypotension, phlebitis, a vasculitis, a heart stop (these reactions are mainly connected with fast infusion of medicine).

from a respiratory system: dispnoe, asthma.

from digestive tract: nausea, vomiting, diarrhea, abdominal pain, pseudomembranous colitis.

from skin and hypodermic fabrics: an itching, urticaria, a dieback, Stephens-Johnson's syndrome, exfoliative dermatitis, IGA - bullous dermatitis, a toxic epidermal necrolysis (very seldom).

to Store

in original packing at a temperature not above 25 °C.

to Store

out of children's reach.