Название документа

Suspension oral Vormil is applied at indications which are provided below.

Intestinal forms of helminthoses and skin syndrome of Larva Migrans (short-term treatment by small doses): an enterobiosis, a dochmiasis and a necatoriasis, a hymenolepiasis, a teniosis, a strongyloidosis, an ascaridosis, a trichuriasis, a clonorchosis, an opisthorchosis, a skin syndrome of Larva Migrans, a giardiasis at children.

System helminthic infections (long-term treatment by high doses):

cystic echinococcosis (caused by Echinococcus granulosus):

  • at impossibility of surgical intervention;
  • before surgical intervention;
  • after operation if preoperative treatment was short if distribution of helminths is observed or during operation found live forms;
  • after carrying out a transdermal drainage of cysts with the diagnostic or therapeutic purpose;

alveolar echinococcosis (caused by Echinococcus multiocularis):

  • in an inoperable disease, in particular in cases of the local or remote metastases;
  • after palliative surgical intervention;
  • after radical surgical intervention or liver transplantation;

neurocysticercosis (caused by Taenia solium larvae):

  • in the presence of single or multiple cysts or at granulematozny damage of a brain;
  • at arachnoidal or intra ventricular cysts;
  • at racemose cysts;

kapillyaroz (the caused Capillaria philippinensis), gnatostomoz (the caused Gnathostoma spinigerum and sibling species), the trichinosis (caused by Trichinella spiralis and T.pseudospiralis), toksokaroz (the caused Toxocara canis and sibling species).

Structure

Acting substance - albendazole (5 ml of suspension contain 200 mg of albendazole).

Excipients: Natrium benzoicum (E 211), xanthane gum, sucrose, sodium methylparaben (E 219), sodium propylparaben (E 217), glycerin, polysorbate 80, dinatrium edetat, dye erythrosine (E 127), aspartame (E 951), citric acid, monohydrate, Crimson Taste fragrance, Fruit Taste fragrance, water purified.

Contraindication

  • hypersensitivity to albendazole, other derivatives of benzylideazoles, to other components of drug;
  • a disease of a retina of an eye;
  • to the women planning pregnancy; women of reproductive age should apply effective non-hormonal contraceptive remedies in time and within the first month after treatment.

Route of administration

to

Dose is established by the doctor individually.

to Children from 1st to 2 years in an enterobiosis, a dochmiasis, a necatoriasis, an ascaridosis, a trichinosis medicament to appoint

on 5 ml of suspension (200 mg) of 1 times a day once.

to Adults and children is more senior than 2 years in an enterobiosis, a dochmiasis, a necatoriasis, an ascaridosis, a trichinosis to use medicament inside on 10 ml of suspension (400 mg) of 1 times a day once.

At the established diagnosis of a strongyloidosis, teniosis and hymenolepiasis to use medicament to adults and children is more senior than 2 years on 10 ml of suspension (400 mg) of 1 times a day within 3 days. In a hymenolepiasis the repeated course of treatment in the range from the 10th in 21st put after the previous course is recommended.

In an opisthorchosis and a clonorchosis to adults and children medicament is more senior than 2 years to appoint 10 ml of suspension (400 mg) 2 times a day within 3 days. The specified scheme is effective also at the mixed invasion of Opisthorhis viverrini and Clonorchis sinensis.

In a giardiasis to children aged from the 2nd up to 12 years to use medicament on 10 ml of suspension (400 mg) of 1 times a day within 5 days.

At a skin syndrome of Larva Migrans to use medicament to adults and children is more senior than 2 years on 10 ml of suspension within 1-3 days.

System helminthic infections (long-term treatment by high doses). To take the medicament together with food. Before use to shake up. Prescribing of medicament in high doses is not recommended to children up to 6 years. The mode of dosing is set individually depending on age, body weight and also severity of an infection. The dose for patients at body weight more than 60 kg makes 400 mg (10 ml of suspension) 2 times a day. At body weight less than 60 kg to appoint medicament at the rate of 15 mg/kg/days. This dose should be divided into 2 receptions. The maximum daily dose - 800 mg.

Recommended use duration:

  • cystic echinococcosis - 28 days (it is possible to appoint a 28-day cycle repeatedly (only 3 times) after a break in 14 days);
  • inoperable and multiple cysts - to 3 28-day cycles at treatment of hepatic, pulmonary and peritoneal cysts (in the presence of cysts of other localization (in bones or a brain) more long-term treatment can be necessary for
  • );
  • to
  • before operation - recommends two 28-day cycles; if operation has to be executed earlier, than these cycles, treatment will be complete to continue as long as possible prior to operation;
  • by
  • after operation, after a transdermal drainage of cysts - if before operation received short (less than 14 days) a course of treatment or in case of performing urgent surgery, after operation to carry out two cycles for 28 days divided by a 14-day break in administration of drug; similarly, if viable cysts are found or there was a distribution of helminths, to carry out two full cycles of treatment;
  • alveolar echinococcosis - 28 days; to repeat the second 28-day year after a two-week break in medicament use; treatment can be prolonged within several months or years;
  • neurocysticercosis - from 7th to 30 days depending on the response to treatment; the second year can be repeated after a two-week break in administration of drug;
  • a cyst in a parenchyma and granulomas - of 7 days (at least) up to 28 days;
  • arachnoidal and intragastric cysts - 28 days;
  • racemose cysts - 28 days, can longer last (duration of treatment is defined by the clinical and radiological response to treatment);
  • a kapillyarioz - 400 mg of 1 times a day within 10 days; usually one course of treatment is required, but the following courses can be necessary if takes of parasitological inspection remain positive;
  • gnatostomoz - 400 mg of 1 times a day within 10-20 days (to see above);
  • a trichinosis, toksokaroz - 400 mg 2 times a day within 5-10 days (to see above).
to

Pregnant

to

Drug is contraindicated to

Feature of use

for use during pregnancy and feeding by a breast and for treatment of the women planning pregnancy. During use of medicament it is necessary to stop feeding by a breast.

Children to

Drug is contraindicated to

for treatment of children aged up to one year. To apply to children according to information specified in the section "Route of administration".

Drivers

Considering existence of such side reaction as dizziness, it is recommended to abstain for use of albendazole from control of motor transport or work with other mechanisms.

Overdose

Symptoms: nausea, vomiting, diarrhea, tachycardia, drowsiness, disorder of vision, visual hallucinations, disturbance of the speech, dizziness, loss of consciousness, increase in a liver, increase in level of transaminases, jaundice; respiratory distress, brown-red or orange coloring of skin, urine, sweat, saliva, tears and excrements in proportion medicament doses.

Treatment: to carry out gastric lavage and to perform symptomatic and maintenance therapy.

Side effects

from a digestive tract and a liver: stomatitis, dryness in a mouth, heartburn, nausea, vomiting, an abdominal pain, a meteorism, diarrhea, a constipation, tranzitorny increase in activity of liver enzymes, jaundice, hepatitis, hepatocellular disturbances.

from a cardiovascular system: increase in arterial blood pressure, tachycardia.

from nervous system and peripheral nervous system: insomnia or drowsiness, headache, dizziness, confusion of consciousness, disorientation, hallucinations, spasms, decrease in visual acuity.

from the system of blood and lymphatic system: leukopenia; neutropenia; thrombocytopenia; anemia, including aplastic anemia; agranulocytosis, pancytopenia. Patients with a liver disease, including hepatic echinococcosis, are more inclined to suppression of marrow.

from skin and hypodermic cellulose: skin rash, hyperaemia, polymorphic erythema, Stephens-Johnson's syndrome, return alopecia, dermatitis, hypostasis.

from kidneys and an urinary system: renal failure, acute renal failure, proteinuria.

Allergic reactions: reactions of hypersensitivity, including rash; itching; small tortoiseshell; bladderwort; dermatitis; fever.

Storage conditions

to Store

in original packing at a temperature not above 25 °C, out of children's reach.

Expiration date - 2 years.

Characteristics
Active ingredients Albendazole
Amount of active ingredient 40 mg/ml
Applicant Mili Healthcare
Code of automatic telephone exchange P02CA03 Albendazole
Interaction with food In time
Light sensitivity Not sensitive
Market status The branded generic
Origin Chemical
Prescription status According to the prescription
Primary packing bottle
Producer GRAKURE PHARMASYYUTIKALS LTD
Quantity in packing 10 ml
Release form suspension for internal use
Route of administration Oral
Sign Import
Storage temperature from 15 °C to 25 °C
Trade name Vormil

Reviews Vormil susp. shouted. 200mg/5ml fl. 10 ml

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Vormil susp. shouted. 200mg/5ml fl. 10 ml

  • Product Code: 182926
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