Tablets are applied to chewing of Vormil at indications which are provided below.

Intestinal forms of helminthoses and skin syndrome of Larva Migrans (short-term treatment by small doses): an enterobiosis, a dochmiasis and a necatoriasis, a hymenolepiasis, a teniosis, a strongyloidosis, an ascaridosis, a trichuriasis, a clonorchosis, an opisthorchosis, a giardiasis at children.

System helminthic infections (long-term treatment by high doses):

cystic echinococcosis (caused by Echinococcus granulosus):

• at impossibility of surgical intervention;
• before surgical intervention;
• after operation if preoperative treatment was short if distribution of helminths is observed or during operation found live forms;
• after carrying out a transdermal drainage of cysts with the diagnostic or therapeutic purpose;

alveolar echinococcosis (caused by Echinococcus multiocularis):

• in an inoperable disease, in particular in cases of the local or remote metastases;
• after palliative surgical intervention;
• after radical surgical intervention or liver transplantation;

neurocysticercosis (caused by Taenia solium larvae):

• in the presence of single or multiple cysts or granulematozny damage of a brain;
• at arachnoidal or intra ventricular cysts;
• at racemose cysts;

kapillyaroz (the caused Capillaria philippinensis), gnatostomoz (the caused Gnathostoma spinigerum and sibling species), the trichinosis (caused by Trichinella spiralis and T.pseudospiralis), toksokaroz (the caused Toxocara canis and sibling species).

Structure

Active ingredient - albendazole (one tablet for chewing contains albendazole 400 mg).

Excipients: corn starch, cellulose microcrystalline, sodium methylparaben (E 219), sodium propylparaben (E 217), sodium krakhmalglikolit (type A), silicon dioxide colloidal anhydrous, talc, magnesium stearate, dry essence of the mixed fruit, aspartame (E 951), sodium lauryl sulfate.

Contraindication

• hypersensitivity to albendazole, other derivatives of benzylideazoles, to other components of drug;
• a disease of a retina of an eye;
• to the women planning pregnancy; women of reproductive age should apply effective non-hormonal contraceptive remedies in time and within the first month after treatment;
• phenylketonuria.

Route of administration

Intestinal infections and a skin syndrome of Larva Migrans

to take the Drug together with food. It is desirable to apply at the same time day. If there does not occur recovery in three weeks, to appoint the second year of treatment.

Tablet can be chewed or crumbed and accepted with a small amount of water.

Recommended dosage:

• enterobiosis, dochmiasis, necatoriasis, ascaridosis, trichuriasis: adults and children aged from 2 years - to 400 mg are 1 times/day (one tablet) once;
• strongyloidosis, teniosis, hymenolepiasis: adults and children aged from 2 years - to 400 mg are 1 times/day (one tablet) within 3 days; in a hymenolepiasis the repeated course of treatment in the range from the 10th in 21st put after the previous course is recommended;
• clonorchosis, opisthorchosis: adults and children aged from 2 years - 400 mg one tablet 2 times a day within 3 days;
• skin syndrome of Larva Migrans: adults and children aged from 2 years - 400 mg one tablet of 1 times a day within 1-3 days;
• giardiasis: only children aged from the 2nd up to 12 years - 400 mg one tablet of 1 times a day within 5 days.

System helminthic infections (long-term treatment by high doses)

to take the Drug together with food. Prescribing of medicament in high doses is not recommended to children up to 6 years. The mode of dosing is set by the doctor depending on age, body weights and also severity of an infection. The dose for patients at body weight more than 60 kg makes 400 mg (one tablet) 2 times a day. At body weight less than 60 kg to appoint medicament at the rate of 15 mg/kg/days. This dose should be divided into 2 receptions. The maximum daily dose - 800 mg.

Recommended use duration:

• cystic echinococcosis - 28 days (it is possible to appoint a 28-day cycle repeatedly (only 3 times) after a break in 14 days);
inoperable and multiple cysts - to 3 28-day cycles at treatment of hepatic, pulmonary and peritoneal cysts (in the presence of cysts of other localization (in bones or a brain) more long-term treatment can be necessary for
• );
to
• before operation - recommends two 28-day cycles; if operation has to be executed before end of these cycles, to continue treatment as long as possible prior to operation;
by
• after operation, after a transdermal drainage of cysts - if before operation received short (less than 14 days) a course of treatment or in case of performing urgent surgery, after operation to carry out two cycles for 28 days divided by a 14-day break in administration of drug; similarly, if viable cysts are found or there was a distribution of helminths, to carry out two full cycles of treatment;
• alveolar echinococcosis - 28 days; to repeat the second 28-day year after a two-week break in medicament use; treatment can be prolonged within several months or years;
• neurocysticercosis - from 7th to 30 days; the second year can be repeated after a two-week break in administration of drug;
• a cyst in a parenchyma and granulomas - of 7 days (at least) up to 28 days;
• arachnoidal and intragastric cysts - 28 days;
• racemose cysts - 28 days, can longer last (duration of treatment is defined by the clinical and radiological response to treatment);
• a kapillyarioz - 400 mg of 1 times a day within 10 days; usually one course of treatment is required, but the following courses can be necessary if takes of parasitological inspection remain positive;
• gnatostomoz - 400 mg of 1 times a day within 10-20 days (to see above);
• a trichinosis, toksokaroz - 400 mg 2 times a day within 5-10 days (to see above).

Pregnant

Drug is contraindicated to

Feature of use

Drug is contraindicated to

for treatment of children aged up to 2 years in this dosage form.

Drivers

Considering existence of such side reaction as dizziness, it is recommended to abstain for use of albendazole from control of motor transport or work with other mechanisms.

Overdose

Symptoms: nausea, vomiting, diarrhea, tachycardia, drowsiness, disorder of vision, visual hallucinations, disturbance of the speech, dizziness, loss of consciousness, increase in a liver, increase in level of transaminases, jaundice; respiratory distress, brown-red or orange coloring of skin, urine, sweat, saliva, tears and excrements in proportion medicament doses.

Treatment: to carry out gastric lavage and to perform symptomatic and maintenance therapy.

Side effects

from a digestive tract: stomatitis, dryness in a mouth, heartburn, nausea, vomiting, an abdominal pain, a meteorism, diarrhea, a constipation, epigastric pain.

Gepatobiliarny disorders: tranzitorny increase in activity of liver enzymes, jaundice, hepatitis, hepatocellular disturbances.

from a cardiovascular system: increase in arterial blood pressure, tachycardia.

from nervous system and peripheral nervous system: insomnia or drowsiness, headache, dizziness, confusion of consciousness, disorientation, hallucinations, spasms, decrease in visual acuity.

from the system of blood and lymphatic system: leukopenia; neutropenia; thrombocytopenia; anemia, including aplastic anemia; agranulocytosis, pancytopenia. Patients with a liver disease, including hepatic echinococcosis, are more inclined to suppression of marrow.

from skin and hypodermic cellulose: skin rash, hyperaemia, polymorphic erythema, Stephens-Johnson's syndrome, return alopecia, (thinning of hair and moderate loss of hair), itching, urticaria, bladderwort, dermatitis, hypostasis.

from kidneys and an urinary system: renal failure, acute renal failure, proteinuria.

to Store

in original packing at a temperature not above 25 °C, out of children's reach.

Expiration date - 3 years.