Vitamin B - 1 solution for infection. 5% of amp. 1 ml No. 10

Solution "Thiamine chlorid-Zdorovye" is applied to injections at the following indications:

• hypo - and B1 vitamin avitaminosis (including at patients who are on probe food, on a hemodialysis, having a sprue);
• as a part of complex therapy: neuritis, polyneurites, sciatica, neuralgia, peripheral paresis and paralysis, neuropathy (diabetic, alcoholic), encephalopathies (including Wernicke-Korsakov's encephalopathy), a neurasthenia, chronic damages of a liver, a myocardial dystrophy, a peptic ulcer of a stomach and duodenum, an intestines atony, an endarteritis, a dermatosis (eczema, atopic dermatitis, a pyoderma, psoriasis, red flat deprive) with neurotrophic changes and disbolism.

Structure

Active ingredient - thiamine (1 ml of solution contains thiamine of a hydrochloride 50 mg).

Excipients: Unithiolum, water for injections.

Contraindication

Hypersensitivity to medicament components, allergic diseases, an idiosyncrasy, the preklimakterichesky and climacteric periods at women.

Route of administration

is Applied intramusculary (deeply in a muscle).

Adult is appointed on 25-50 mg (0.5-1 ml of drug) of 1 times a day, daily. Introduction is begun with small doses - no more than 25 mg (0.5 ml); higher doses - 50 mg (1 ml) enter only at good tolerance. A course of treatment - 10-30 injections.

In Wernicke-Korsakov's encephalopathy are applied on 50-100 mg (1-2 ml) by 2 times a day before clinical improvement. It is necessary to consider a likelihood of development of allergic reaction to administration of B1 vitamin.

to Children 2.5% usually apply hydrochloride thiamine solution. Administration of medicament in this dosage (5% of solution) to children aged from 8 years is possible, appoint 12.5 mg (0.25 ml) of 1 times a day, daily. A course of treatment - 10-30 injections.

Feature of use

Pregnant

Use of medicament during pregnancy and feeding by a breast perhaps under observation of the doctor according to indications in the recommended doses.

Drivers

during treatment should be careful at control of vehicles and work with mechanisms in connection with a possibility of development of side reactions from nervous system.

Overdose

Symptoms: strengthening of symptoms of side effect of medicament is possible. Development of hypercoagulation, disturbance of purine exchange is not excluded.

Treatment: medicament withdrawal, symptomatic therapy.

Side effects

from a cardiovascular system: tachycardia, heartbeat, collapse.

from nervous system: headache, dizziness, concern, paresthesias.

from organs of sight: damage of an optic nerve.

from a respiratory system: the complicated breath, an asthma.

from a digestive tract: the complicated swallowing, nausea, intestinal hemorrhages.

from the immune system: rash, an itching (including in the place of an injection), dermatitis, hyperaemia, urticaria, a Quincke's disease, a bronkhospastichesky syndrome with spasms, an acute anaphylaxis.

from digestive system: disturbance of activity of enzymes of a liver.

Interaction

should not be mixed with solutions which contain sulfites, to niacin - there is a thiamine destruction; to benzylpenicillin or streptomycin - there is a destruction of antibiotics; with carbonates, citrates, barbiturates, with Cu ²⁺ , iodides, tannin acid - thiamine is unstable in alkaline and neutral solutions.

to Store

in original packing at a temperature not above 25 °C, out of children's reach.

Expiration date - 3 years.