VetExpert KalmVet (KalmVet) Soothing medicine for Pokazaniyas animals to application: The product is intended for removal of symptoms of a stress and concern at animals. Properties: Tryptophane is an amino acid, is a predecessor of a neurotransmitter of serotonin. Increase in amount of tryptophane in a diet leads to increase in its concentration in a brain that increases production of serotonin which at hit in synoptic cracks can interact with various subtypes of receptors. Affecting these receptors in various parts of a brain, serotonin controls many physiological functions, such as: release of hormones, pain, appetite, mood of an animal and behavior. In researches which were conducted on dogs it was revealed that increase in level of serotonin in a brain can reduce aggression manifestations, itself damages and increase resistance of dogs to a stress. Chamomilla recutita between various biological properties has the calming property. Apigenin who is contained in camomile extract interacts with benzodiazepinovy receptors and shows ability to eliminate concern and possesses the calming action. Such action was confirmed on patients - animals with the general uneasiness. Except an apigenin in extract of a camomile there are also other connections which interact with benzodiazepinovy and scale - aminomaslyanokislotnima (GAMK) receptors in a brain and, thus, provide the calming effect of extract of a camomile. The valerian, namely extract of active agents with Valeriana officinalis, is known many years for the properties to eliminate concern and uneasiness. The mechanism of action of a valerian consists in presence of terpenic communications, mainly valerian and piperidic (GAMK) of acids. Active agents which can be found in extract interact with many receptors of neurotransmitters including with 5-HT-5A receptor which takes part in regulation of feeling of alarm. The calming effect of extract of a valerian was confirmed in many researches on animals and people. date editing description: 02.08.2021