Pharmacological properties

Use of the high-concentrated urea medicaments in treatment of dermatological diseases is based, first of all, on keratoplastichesky influence of urea. besides, skin appliques of the concentrated medicaments of urea increase liquid content in a corneal layer of epidermis of the person. urea is the natural moistening means which improves binding of water in the upper layers of the skin and reduces its loss by epidermis. the efficiency of similar means in treatment of an ichthyosis, psoriasis and positive impact at patients with dry and sensitive skin is proved. urea has low molecular weight thanks to what it is quickly soaked up. along with hydration properties, urea renders keratolytic effect therefore there is a fast softening of skin and flaking of firm scales.

Excipients which are a part of ointment hold active ingredient (urea) in the site of application, thereby interfering with its absorption in a system blood stream. Discharge of the absorbed urea is carried out through urine and in insignificant quantities — through sweat.

Indication

it Is applied to treatment of neurodermatitis (including at elderly people) and also as supportive application at treatment of an ichthyosis.

with

1–2 times a day, before reduction of expressiveness of symptoms, on carefully cleaned dry skin, intensively rubbing. the occlusive bandage is used on doctor's orders. clinical information concerning ointment use ureotop more than 3 weeks is absent.

Contraindication

Hypersensitivity to propylene glycol or any component of drug. do not apply to treatment of an acute inflammation of skin.

Side effects

According to the obtained data, emergence of side effects is classified as follows:

Infrequently allergic reactions to the substances which are a part of this medicine, in particular irritations of skin, such as burning, reddening, itching or peeling can note.

If some of the given side effects significantly is worsened by a state or if there is a side effect which is not specified in the instruction it is necessary to report about it to the doctor.

to Avoid

hits of ointment on mucous membranes, not to put around eyes as it can lead to their irritation. not to apply to treatment of an acute inflammation of the injured skin. at accidental ingestion of a large amount of medicament and emergence of symptoms of intoxication it is necessary to see a doctor.

Use during pregnancy and feeding by a breast. Data on use of the medicament Ureotop during pregnancy or feeding by a breast are absent therefore administration of medicament during this period is not recommended.

Children. Data relatively of use of Ureotop ointment for children are absent therefore medicine is not applied in pediatric practice.

Ability to influence speed of response at control of vehicles or work with other mechanisms. Does not influence.

raised resorption skin of other locally put means Is possible

Interaction (especially gks). simultaneous use of other medicaments containing urea or its derivatives is not recommended.

Overdose

Given about cases of overdose are absent.

Storage conditions

At a temperature not above 25 °C. after the first opening of a tuba an expiration date of 6 months