Tselista Ot of a sore throat - non-steroidal anti-inflammatory medicament which shows powerful anti-inflammatory, anesthetizing and febrifugal for short-term symptomatic pain relief in a throat at adults and children aged from 12 years.

Structure

• active ingredient: flurbiprofen;
• 1 lollipop supports a flurbiprofen of 8.75 mg;
• other components: sucrose, glucose solution, macrogoal 300, peppermint oil, left menthol.

Contraindication

• Hypersensitivity to a flurbiprofen or any of medicine excipients.
• Existence in the anamnesis of hypersensitivity reactions (for example, bronchial asthma, a bronchospasm, rhinitis, a Quincke's disease or a small tortoiseshell) after intake of acetylsalicylic acid or other non-steroidal anti-inflammatory medicaments (NPVS).
• Recurrent peptic ulcer / bleeding in the anamnesis or in an aggravation phase (two or more episodes confirmed with characteristic clinical manifestations) and intestines ulcers.
• Gastrointestinal bleeding or perforation in the anamnesis, colitis with a heavy course, the hemorrhagic or hemopoietic frustration connected with preliminary therapy of NPVS.
• Last trimester of pregnancy.
• Heavy heart failure, heavy renal failure or heavy liver failure.

to

about reactions of hypersensitivity to NPVS which can include:

• nonspecific allergic reactions and anaphylaxis;
• reactivity of airways, for example: bronchial asthma, exacerbation of bronchial asthma, bronchospasm, short wind;
• various reactions from skin, for example: the itch, urticaria, a Quincke's disease, are more rare an exfoliative and bullous dermatosis (including an epidermal necrolysis and a multiformny erythema).

Due to the treatment of NPVS was reported about such phenomena as hypostasis, arterial hypertension and heart failure. Clinical trials and epidemiological data demonstrate that application of some NPVS (especially in high doses and long-term treatment) can be associated with a little increased risk of arterial trombotichesky complications (for example, a myocardial infarction or a stroke).

Route of administration

Lollipops to rassasyvat

before full dissolution. To adults and children aged from 12 years to accept on 1 lollipop each 3–6 hours before pain relief. The maximum daily dose makes 5 lollipops.

to Apply a low effective dose during the least long period necessary for relief of symptoms. If symptoms do not disappear, more than 3 days worsen or proceed, it is necessary to see a doctor.

does not recommend to apply medicine more than 3 days.

should move with

At resorption lollipop on all oral cavity for prevention of irritation mucous in the place of resorption.

Feature of application

Use during pregnancy or feeding by a breast

Inhibition of synthesis of prostaglandins can have negative impact on pregnancy and/or development of an embryo/fruit.

during ІІІ a pregnancy trimester.

In some researches flurbiprofen it was found in breast milk in very low concentration. It is improbable that it had negative impact on the nursing baby. However because of possible undesirable effects of NPVS on the nursing babies the women nursing are not recommended to apply medicine.

not to apply

to children up to 12 years.

Ability to influence speed of response at control of motor transport or other mechanisms

Research of ability to influence speed of response at control of motor transport or other mechanisms was not conducted by

.

Overdose

Symptoms. Use of clinically significant quantity of NPVS made most of patients only sick, vomiting, pain in epigastric area or is more rare – diarrhea. Also there can be a sonitus, headaches and gastrointestinal bleeding. In more serious poisoning toxic damages of the central nervous system in the form of drowsiness, sometimes – excitement, a disorder of vision, a disorientation or a coma are possible.

Treatment. Treatment has to be symptomatic and supporting and also to include ensuring passability of airways and monitoring of warm function and key indicators of activity to normalization of a condition of the patient. Oral administration of activated carbon during 1 h after application of potentially toxic medicament dose is recommended. At frequent or long spasms of muscles the treatment should be carried out by intravenous administration of diazepam or lorazepam. In bronchial asthma it is necessary to apply bronchodilators. There is no specific antidote to a flurbiprofen.

Interaction with other medicines and other types of interactions

Should avoid simultaneous application of a flurbiprofen with other NPVS; acetylsalicylic acid.

Should be applied with care flurbiprofen in combination with the following medicines: anticoagulants: NPVS can enhance effect of such anticoagulants as warfarin; antithrombocytic means: the risk of developing of a gastrointestinal ulcer or bleeding increases; antihypertensive medicaments (diuretics, APF inhibitors and antagonists of angiotensin II; alcohol: increases risk of side reactions, especially bleedings in digestive tract; cardiac glycosides:; cyclosporine: the increased risk of nephrotoxicity; corticosteroids: increase risk of emergence of side reactions, in particular digestive tract; lithium: increase in level of lithium in blood serum, appropriate control and if necessary dose adjustment is possible; methotrexate: application of NPVS within 24 hours to or after application of a methotrexate can lead to increase in concentration of a methotrexate and increase in its toxic action; mifepristone: it is not necessary to accept NPVS within 8-12 days after use of mifepristone as NPVS can reduce effect of mifepristone; oral anti-diabetic means: glucose level in blood can change (strengthening of control of level of glucose in blood is recommended).

to Store

in original packing at a temperature not above 30 °C. To store out of children's reach.