Powder for injections Tsefepim of Yury-pharmaceutical is applied to solution at indications which are provided below.

Adults (the infections caused by microflora, sensitive to drug):

• respiratory infection, including pneumonia;
• uncomplicated infections of leather and hypodermic cellulose;
• complicated intraabdominal infections (it is applied in a combination with metronidazole);
• uncomplicated and complicated infections of urinary tract (including pyelonephritis);
• septicaemia;
• empirical therapy of patients with neytropenichesky fever;
• prevention of postoperative complications in intraabdominal surgery.

Children:

• pneumonia;
• an infection of urinary tract, including pyelonephritis;
• an infection of leather and hypodermic cellulose;
• empirical therapy of patients with neytropenichesky fever;
• bacterial meningitis.

Structure

Active ingredient: tsefepy (1 bottle supports a tsefepim of a hydrochloride in terms of tsefepy 1 g).

Excipient - L-arginine.

Contraindication

Hypersensitivity to a tsefepim or arginine and also to antibiotics of a tsefalosporinovy class, penicillin or other β-laktamny antibiotics.

Route of administration

Before use of medicine needs to take skin samples on shipping.

Usual dose for adults makes 1 g which is entered intravenously or intramusculary at an interval of 12 hours. The usual duration of treatment - 7-10 days; heavy infections can demand more long-term treatment.

depending on sensitivity of microorganisms activators, severity of an infection and also a functional condition of kidneys of the patient.

gave a fact-finding part of the instruction, read the full instruction in packing.

Feature of application

Pregnant women

Test on animals lack of impact on reproductive function and lack of any harmful effects on a fruit, however adequate and well controlled researches among pregnant women were not conducted therefore tsefepy during pregnancy it is possible to appoint only when the expected advantage for mother exceeds potential risk for a fruit.

In a small amount tsefepy gets into breast milk therefore during medicament treatment the feeding by a breast should be stopped.

Children

to use Drug to children aged from the 1st month.

At use of lidocaine as solvent should consider information on safety of lidocaine.

in case of prescribing of medicine to children aged from the 1st month the doctor has to estimate carefully a dose depending on age, weight, severity and type of an infection; conditions of function of kidneys.

Drivers

As during treatment can arise side reactions from the central nervous system, it is necessary to abstain from control of motor transport or work with mechanisms.

Overdose

Symptoms

in case of considerable exceeding the recommended doses, especially at patients with impaired renal function, amplify manifestations of side effect. Symptoms of overdose include encephalopathy that is followed by hallucinations, consciousness violations, a stupor, a coma, a myoclonia, epileptoformny attacks, neuromuscular irritability.

Treatment

Should stop medicine introduction, to carry out symptomatic therapy. Use of a hemodialysis accelerates removal of a tsefepim from an organism; peritoneal dialysis is ineffective. Heavy allergic reactions of immediate type demand use of adrenaline and other forms of intensive care.

Side reactions are observed by

seldom.

Storage conditions

to Store

in original packing at a temperature not above 25 °C, out of children's reach.

Ready solutions of medicine are stable

within 7 days at a temperature of storage of 2-8 °C.

Expiration date - 2 years.