A tree About gel it is shown for topical treatment of ordinary eels (acne vulgaris).

Structure

Active ingredients: adapalen, clindamycin;

1 g of gel the adapalena of 1 mg, clindamycin (in the form of phosphate clindamycin) contains 10 mg;

Excipients: sodium edetat, carbomer 940, propylene glycol, methylparaben (E 218), half-oxameasures 407, phenoxyethanol, sodium hydroxide, water purified.

Contraindication

• Hypersensitivity to an adapalen or other components of medicine.
• Enteritis, ulcer colitis, colitis associated with antibiotics (in the anamnesis), Crohn's disease.

Route of administration

adults and children should use Drug 12 years are more senior.

Gel is applied a thin layer to clean dry skin in places of rashes of 1 times a day, for the night.

earlier. In that case it is not necessary to stop treatment, the therapeutic effect is observed in 8-12 weeks from an initiation of treatment.

Pregnant

not to apply

Feature of application

Safety and efficiency of use of medicine for children aged up to 12 years were not investigated by

therefore children of this age category should not use drug.

Drivers

does not influence.

When putting gel in excess quantity the reddening and peeling of skin is possible

.

Side effects

Reddening, peeling, dryness, an itch and burning of skin in the site of application of gel right after its drawing which takes place further. Allergic reactions, a photosensitization, an acne, feeling of pricking, gram-negative a folliculitis, gastrointestinal disorders, an abdominal pain, urticaria, the increased skin oiliness, contact dermatitis, burning of eyes, are occasionally observed side reactions in the form of diarrhea, diarrhea with impurity of blood and colitis (including pseudomembranous colitis).

Interaction

As Deriva water gel can cause the local irritating effect in some patients, simultaneous use of other potentially irritating local medicines, including cosmetics, increases risk of undesirable impact on skin.

with care medicine with the medicines containing sulfur, resorcin or salicylic acid.

Klindamitsin has property to block neuromuscular transmission that can lead to strengthening of effect of other medicines with similar properties. Therefore it should be applied with care to patients who receive such medicines. There is a cross stability between clindamycin and lincomycin. Also it was noted antagonism between erythromycin and clindamycin.

to Store

at a temperature not above 25 °C.

to Store

out of children's reach.

not to freeze

.

Expiration date - 2 years.