Dvatsa 200 Hot Drink – the means applied at cough and catarrhal diseases. Mucolytic means for treatment of the sharp and chronic diseases of a bronchopulmonary system which are followed by the increased formation of a phlegm.

Structure

• active ingredient: acetylcysteine;
200 mg contain
• 1 sachet Acetylcysteinum;
• other components: sorbitol (E 420), to potassium atsesulfa, fragrance orange.

for

hypersensitivity to Acetylcysteinum or any of medicine excipients Is known to

Contraindication

. A peptic ulcer of a stomach and duodenum in an aggravation stage, a pneumorrhagia, pulmonary bleeding, heavy exacerbation of bronchial asthma.

Side reactions

from organs of hearing and a vestibular mechanism: seldom – a ring in ears.

from the respiratory system, bodies of a thorax and mediastinum: seldom - dispnoe, a bronchospasm (mainly at patients with hyperreactivity of a bronchial system which is associated with bronchial asthma); frequency is unknown – a rhinorrhea.

from digestive tract: seldom – heartburn, stomatitis, abdominal pain, nausea, vomiting, diarrhea; seldom – dyspepsia; frequency is unknown – an unpleasant smell from a mouth.

from nervous system: infrequently – a headache.

from a cardiovascular system: infrequently – tachycardia, decrease in the ABP; very seldom – hemorrhages.

from blood and lymphatic system: frequency is unknown – anemia.

from the immune system: seldom – hypersensitivity; very seldom - an acute anaphylaxis, anaphylactic/anaphylactoid reactions.

from skin and hypodermic cellulose: infrequently – an itch, urticaria, a dieback, rash, a Quincke's disease (Quincke's edema); frequency is unknown – eczema.

Route of administration

Adults and children aged from 12 years - 400-600 mg the day distributed on 1-3 receptions.

Children

• 2-6 years: 200–400 mg the day distributed on 1–2 receptions;
• 6-12 years: 400–600 mg the day distributed on 2–3 receptions;
• age of 12 years – doses, as for adults.

Is recommended to be accepted after a meal.

Contents of a bag to dissolve

when stirring in ½ glasses of cold water, then to add the hot, but not boiling water to a full glass. To drink solution after cooling up to the acceptable temperature, but not later than in 30 minutes after preparation. The sequence of dissolution of powder (at first to add cold water, and then hot) should not change.

At dissolution of Acetylcysteinum needs to use glasswares, to avoid contact with metal and rubber surfaces.

Additional use of liquid enhances mucolytic effect of medicine.

Duration of a course of treatment is defined by the doctor individually depending on the nature of a disease. In sharp uncomplicated diseases to apply Acetylcysteinum of 4-5 days.

Use during pregnancy or feeding by a breast

Clinical data on use of Acetylcysteinum to pregnant women are limited to

Feature of application

. Researches had no direct or indirect negative impact on pregnancy, embriofetalny development, childbirth and post-natal development on animals.

Information on penetration of Acetylcysteinum into breast milk is absent.

it is necessary to Apply medicine during pregnancy or feeding by a breast only after careful assessment of a ratio advantage/risk.

Children

to Apply

to children of 2 years.

Ability to influence speed of response at control of motor transport or other mechanisms

Is not present confirmation that Acetylcysteinum affects ability to drive the car and other mechanisms.

Overdose

Is not present data on overdose cases at oral administration of Acetylcysteinum.

Adult volunteers accepted 11.6 g of Acetylcysteinum a day within three months without any serious side effects.

Acetylcysteinum at application in a dose of 500 mg/kg/days does not cause overdose.

Symptoms.

Overdose can be shown by gastrointestinal symptoms, such as nausea, vomiting and diarrhea. Children have a risk of hypersecretion.

Treatment.

is not present

Specific antidote at poisoning with Acetylcysteinum, therapy symptomatic.

Interaction with other medicines and other types of interactions is not recommended to

by

dissolution in one glass of Acetylcysteinum with other medicines.

Researches of interaction were conducted by

only with participation of adults.

Use together with Acetylcysteinum of antibechics can increase stagnation of a phlegm because of oppression of a tussive reflex.

Activated carbon reduces efficiency of Acetylcysteinum.

At simultaneous application with such antibiotics as tetracyclines (except for doxycycline), ampicillin, Amphotericinum B, cephalosporins, aminoglycosides their interaction with thiol group of Acetylcysteinum is possible

that leads to decrease of the activity of both medicines. Therefore the interval between use of these medicines has to be not less than 2 hours. It does not concern a tseffix and a lorakarbef.

by

At a concomitant use of nitroglycerine and Acetylcysteinum found considerable hypotensions and expansion of a temporal artery. In need of simultaneous use of nitroglycerine and Acetylcysteinum for patients it is necessary to control hypotension which can have difficult character, it is also necessary to consider possibility of headaches.

by

recorded synergism of Acetylcysteinum with bronchial spasmolytics.

Atsetiltsistein can be the donor of cysteine and increase the level of the glutathione promoting a detoxication of free radicals of oxygen and certain toxics in an organism.

Storage conditions

to Store

in original packing at a temperature not above 25 °C.

to Store

out of children's reach.