tablets Albendazole are applied at indications which are provided below.

Intestinal forms of helminthoses and skin syndrome of Larva Migrans (short-term treatment by small doses): an enterobiosis, a dochmiasis and a necatoriasis, a hymenolepiasis, a teniosis, a strongyloidosis, an ascaridosis, a trichuriasis, a clonorchosis, an opisthorchosis, a giardiasis at children.

System helminthic infections (long-term treatment by high doses):

• Cystic echinococcosis (caused by Echinococcus granulosus):
  • at impossibility of surgical intervention;
  • before surgical intervention;
  • after operation if preoperative treatment was short if distribution of helminths is observed or during operation found live forms;
  • after carrying out a transdermal drainage of cysts with the diagnostic or therapeutic purpose;
• Alveolar echinococcosis (caused by Echinococcus multiocularis):
  • in an inoperable disease, in particular in cases of the local or remote metastases;
  • after palliative surgical intervention;
  • after radical surgical intervention or liver transplantation;
• Neurotsistitserkoz (called by Taenia solium larvae):
  • in the presence of single or multiple cysts or granulematozny damage of a brain;
  • at arachnoidal or intra ventricular cysts;
  • at racemose cysts;
• Kapillyaroz (called by Capillaria philippinensis), gnatostomoz (the caused Gnathostoma spinigerum and sibling species), the trichinosis (caused by Trichinella spiralis and T.pseudospiralis), toksokaroz (the caused Toxocara canis and sibling species).

Structure

Active ingredient: albendazole;

1 chewable tablet contains albendazole 400 mg;

Excipients: corn starch, cellulose microcrystalline, sodium krokhmalglikolit, silicon dioxide colloidal anhydrous, fragrance orange, aspartame, talc, magnesium stearate.

Contraindication

• Hypersensitivity to albendazole, other derivatives of benzylideazoles, to other components of drug.
• Disease of a retina of an eye.
• Period lasting one menstrual cycle before the planned pregnancy.
• Phenylketonuria.

Route of administration

Drug is taken along with food. It is desirable to apply at the same time day. If there does not occur recovery in three weeks, the second year of treatment is appointed.

Tablet can be chewed or crumbed and accepted with a small amount of water.

Pregnant

Drug is contraindicated to

Feature of use

Drug is contraindicated to

for treatment of children under 3 years in this dosage form.

Drivers

Considering existence of such side reaction as dizziness, it is recommended to refrain for use of albendazole from control of motor transport or work with other mechanisms.

Overdose

Symptoms: nausea, vomiting, diarrhea, tachycardia, drowsiness, disorder of vision, visual hallucinations, disturbance of the speech, loss of consciousness, increase in a liver, increase in level of transaminases, jaundice; a respiratory distress, brownish-red or orange coloring of skin, urine, sweat, saliva, tears and excrements it is proportional to a medicament dose.

Treatment: carry out gastric lavage and perform symptomatic and maintenance therapy.

Side effects

• from a digestive tract and a liver: stomatitis, dryness in a mouth, heartburn, nausea, vomiting, an abdominal pain, a meteorism, diarrhea, a constipation.
• Gepatobiliarny disorders: tranzitorny increase in activity of liver enzymes, jaundice, hepatitis, hepatocellular disturbances.
• from a cardiovascular system: increase in arterial blood pressure, tachycardia.
• from the central nervous system and peripheral nervous system: insomnia or drowsiness, headache, dizziness, confusion of consciousness, disorientation, hallucinations, spasms, decrease in visual acuity.
• from the system of blood and lymphatic system: a leukopenia, a neutropenia, thrombocytopenia, anemia, including aplastic anemia, an agranulocytosis, a pancytopenia. Patients with a liver disease, including hepatic echinococcosis, are more inclined to oppression of marrow.
• from skin and hypodermic cellulose: skin rashes, hyperaemia, polymorphic erythema, Stephens's syndrome ― Johnson, return alopecia, itching, small tortoiseshell, bladderwort, dermatitis, hypostasis.
• from kidneys and an urinary system: renal failure, acute renal failure, proteinuria.
• General disorders: bone, throat pain, fever, weakness.

Interaction

At simultaneous use of albendazole with theophylline should control theophylline level in blood.

Systemic action increases if to take the medicament at meal time.

Grapefruit juice also increases albendazole sulphoxide level in blood plasma.

Because of possible disturbance of activity of P450 cytochrome the theoretical risk of interaction with such medicaments exists: oral contraceptives, anticoagulants, oral antihyperglycemic means, theophylline.

to Store

in original packing at a temperature not above 25ºС.

to Store

out of children's reach.

Expiration date - 3 years.