Pharmacological properties

Solution of sodium of chloride of 0.9% izotonichen to blood plasma of the person. sodium chloride which comes to an organism in necessary quantity with food gets to blood and to intercellular liquid at the expense of what the constant osmotic pressure of blood and intercellular liquid is substantially supported. at deficiency of sodium and chlorine owing to their strengthened elimination caused by the long expressed diarrhea, extensive burns, pernicious vomiting, hypofunction of bark of adrenal glands and other morbid conditions there is a haemo concentration owing to transition of water from blood in fabric. at significant deficit there are spasms smooth and convulsive reductions of skeletal muscles, function of cardiovascular and nervous systems is broken. isotonic solution of sodium of chloride fills otsk in the blood channel at its decrease, normalizes ionic balance. has disintoxication effect. does not render irritant action at various ways of introduction. isotonic solution of sodium of chloride is applied also to dissolution of medicines.

Indication

Toxic dyspepsia, pernicious vomiting, cholera, poisonings, sharp blood loss, shock, the postoperative period, etc. outwardly at various diseases of eyes, a nose, mucous membranes, for washing of wounds.

Use

In/in, p / to, rektalno (enemas). more sterile solution is most often entered in/in by drop infusion in volume from 5–10 ml to 2 l. at cholera, during the postoperative period, at toxic dyspepsia the volume of the entered solution can reach 3 l/days at p / to introduction the volume of solution depends on indications.

are entered by 75–100 ml of solution. For washing of eyes, a nose, wounds also use sterile solution.

Contraindication

In/in introduction it is contraindicated at thrombophlebitises, conditions of hypercoagulation, a serious illness of kidneys, at dekompensirovanny heart diseases. it is not necessary to pour in isotonic solution of sodium of chloride at circulator violations which are capable to cause edematization of lungs and a brain, at a hypernatremia.

At introduction in large volume can lead

to development of chloride acidosis, the strengthened elimination of potassium and a hypopotassemia, an overhydratation. at development of the specified complications the introduction of medicine is cancelled.

Special instructions

Due to the fast removal of isotonic solution of sodium of chloride from a vascular bed at a state of shock and blood loss for compensation of its insufficient efficiency hemotransfusions, pour plasma and plasma substituting means. at long introduction of isotonic solution of sodium of chloride, especially in large volumes, control the content of electrolytes in blood plasma and urine, a diuresis. with care enter the patient with violation of secretory function of kidneys.

Interaction

should not pour in chloride sodium solution at simultaneous application gks in high doses.

Storage conditions

At the room temperature.