Promotsef to apply powder for solution for injections to treatment of infections which causative agents are sensitive to a tseftriakson:

• respiratory infection, especially pneumonia and also infections of an ear, throat and nose;
• an infection of abdominal organs (peritonitis, infections of biliary tract and digestive tract);
• an infection of kidneys and urinary tract;
• an infection of genitals, including gonorrhea;
• sepsis;
• an infection of bones, joints, soft tissues, skin and also wound fevers;
• an infection at patients with the weakened immunity;
• meningitis;
• disseminate borreliosis of Lyme (stages of II and III).

Structure

Active ingredient: ceftriaxone;

1 bottle supports a tseftriakson (in the form of a tseftriakson of sodium) 1.0 g

Contraindication

Hypersensitivity to a tseftriakson or to any other cephalosporin. Existence in the anamnesis of heavy reactions of hypersensitivity (for example, anaphylactic reactions) to any other type beta laktamnykh antibacterial agents (penicillin, monobaktam and karbapenem).

:

• premature newborn aged ≤ 41 weeks taking into account the term of pre-natal development (gestational age + age after the birth);
• full-term newborn (aged ≤ 28 days):
• with a hyperbilirubinemia, jaundice, a hypoalbuminemia or acidosis as at such states the bilirubin binding is probably broken;
• who demand (or it is expected that will demand) administration of medicines of calcium or infusions of kaltsiysoderzhashchy solutions as there is a risk of formation of precipitated calcium superphosphates of calcic salt of a tseftriakson.

Route of administration

to Adults and children is more senior than 12 years: to apply 1 – 2 g of a tseftriakson of 1 times a day (each 24 hours). In heavy infections or infections which causative agents have only moderate sensitivity to a tseftriakson it is possible to increase a daily dose to 4 g

Newborns, babies and children aged to 12 years.

give the recommended doses for application of 1 times a day Below.

Newborn (up to 2 weeks): 20 – 50 mg/kg of body weight of 1 times a day, the daily dose should not exceed 50 mg/kg of body weight. Medicine doses for the full-term and premature children do not differ.

for application by the newborn aged ≤ 28 days if necessary (or the expected need) treatments by intravenous solutions, calciferous (including constant intravenous injections which contain calcium, for example, parenteral nutrition), in connection with risk of emergence of precipitated calcium superphosphates of calcic salts of a tseftriakson (see the section "Contraindications").

Feature of application

Pregnant

during pregnancy, especially in the first trimester, tseftriakson it is possible to apply, only if the advantage exceeds risk.

Children

use Drug to children according to a dosage.

Corresponding researches were not conducted by

. Due to the possibility of such side reactions as dizziness, tseftriakson can affect ability to steer vehicles or to work with difficult mechanisms.

Overdose

in case of overdose the hemodialysis or peritoneal dialysis will not reduce excessive concentration of medicine in blood plasma. In case of overdose the nausea, vomiting, diarrhea can be observed. Specific antidote does not exist. Overdose treatment symptomatic.

Side effects

Undesirable reactions which were most often observed at application of a tseftriakson are an eosinophilia, a leukopenia, thrombocytopenia, diarrhea, rash and increase in level of liver enzymes.

Interaction

Solvents, calciferous, such as Ringera solution or Gartman's solution, it is not necessary to use for restoration of medicine in bottles or for further cultivation of the restored solution for intravenous administration as precipitated calcium superphosphate can be formed.

Tseftriakson, as well as other antibiotics, can serve as the reason of false positive results of the analysis on a galactosemia.

to Store

out of children's reach in original packing at a temperature not above 25 °C.

Expiration date - 3 years.