Indications of Omeprazol-Darnitsa is a benign stomach ulcer and an ulcer of a duodenum, including it is connected with intake of non-steroidal anti-inflammatory drugs; Helicobacter pylori eradikation (as a part of combination therapy with antibacterial agents); gastroesophageal reflux disease; prevention of aspiration of acid contents of a stomach; Zollingera-Ellison's syndrome, weakening of symptoms kislotozavisimy dyspepsias.

Structure

Active ingredient: omeprazole.

1 capsule contains pellet omeprazolum (in terms of omeprazolum) 20 mg.

Excipients: mannitol (E421), gipromelloza, methacrylate copolymer dispersion, sodium lauryl sulfate, sodium phosphate waterless, diethyl phthalate, sucrose, titan dioxide (E 171), povidone, calcium carbonate, talc, polysorbate 80, sodium hydroxide.

Contraindication

Hypersensitivity to omeprazolum, to the substituted benzimidazoles or to other components of medicine. Omeprazolum, as well as other inhibitors of the proton pump, it is not necessary to accept together with nelfinaviry and atazanaviry.

Route of administration

Inside before or at meal time, without chewing and without damaging the capsule, washing down with a small amount of liquid. The mode of dosing depends on a look and disease severity and is established individually for each patient.

Feature of application

At emergence at patients with stomach ulcer or suspicion of stomach ulcer of such disturbing symptoms as the considerable decrease in body weight which is not caused by a diet frequent vomiting, a dysphagy, vomiting with impurity of blood or ground, it is necessary to exclude presence of a malignant disease as intake of medicine can mask its symptoms and delay definitions of the diagnosis.

Pregnant

Results of researches did not reveal negative impact of omeprazolum during pregnancy on health of the fruit/newborn. Medicine can be applied during pregnancy if, according to the doctor, the expected advantage for mother exceeds possible risk for a fruit.

in insignificant quantity in breast milk, but its influence on the child is unknown. Therefore it is necessary to stop feeding by a breast for use of medicine.

Children

apply Medicine to children 5 years on doctor's orders according to indications a reflux esophagitis and symptomatic treatment of heartburn and an acid eructation are more senior at a gastroesophageal reflux disease and for treatment of an ulcer of the duodenum caused by existence of H.pylori under control of the doctor.

Drivers

Influence of medicine on ability to steer motor transport or it is improbable to work with mechanisms, but it is necessary to consider possibility of side reactions as dizziness and a disorder of vision.

very limited data on effects of overdose of omeprazolum at the person Are known to

. In literature also the received single messages about achievement of a single oral dose of 2400 mg of omeprazolum were described a dosage up to 560 mg of omeprazolum (is 120 times higher than the usual recommended clinical dose). It was reported about nausea, vomiting, dizziness, an abdominal pain, diarrhea and a headache. It was also in rare instances reported about apathy, a depression and confusion of consciousness.

Described symptoms have passing character. Speed of a conclusion does not change (kinetics of the first order) with increase in a dose.

Treatment. There is no specific antidote. It is badly removed by means of dialysis. Gastric lavage, symptomatic and maintenance therapy.

Side reactions

Most frequent side effects are a headache, an abdominal pain, a lock, diarrhea, an abdominal distension, nausea / vomiting.

Interaction

Medicines which absorption depends from rn a stomach.

Oppression of gastric secretion at treatment by omeprazolum and other medicines from the INN group (inhibitors of the proton pump) can reduce or increase absorption of medicines which absorption depends from rn a stomach. As well as in a case with other medicines reducing intragastric acidity the absorption of such medicines as ketokonazol, itrakonazol and also erlotinib can decrease whereas absorption of such medicines as digoxin can increase at medicament treatment. Simultaneous use of omeprazolum (20 mg/days) and digoxin at healthy volunteers increased bioavailability of digoxin by 10% (in two of ten studied persons - up to 30%).

to Store

in original packing at a temperature not above 25 °C. To store out of children's reach.

Expiration date - 2 years.