Msd Animal Heals of Pozatex of a drop ear, suspension for Opisaniyes dogs: Suspenziya white Structure color: 1 ml of medicine contains active ingredients: orbifloksatsin - 8.5 mg, a mometazona furoat (monohydrate) - 0.9 mg, pozakonazol - 0.9 mg, excipients: mineral oil (liquid paraffin) Pharmacological properties: Automatic telephone exchange of vet classification QS02CA91 code - veterinary medicines which apply in otology, mometazon and protimikrobny Orbifloksatsin - a synthetic bactericidal antibiotic of a broad spectrum of activity that belongs to group of hinolon derivatives of the carbonic acid known as ftorkhinolona. Oppressing two enzymes of a microbic Cage - DNA-topoisomerase II (DNK-girazu) and DNA topoisomerase IV, orbifloksatsin breaks synthesis of bacterial DNA what to make to the termination of replication and fast death of a microbic cage. SPEED of Action and degree bactericidal activities a dose are dependent. In vitro, orbifloksatsin shows a temple Activity against a wide range of gram-positive and gram-negative microorganisms (koagulazo-Polozhitelnye staphylococcus (Staphylococcusspp.), Pseudomonasaeruginosa, Enterococcusfaecalis) Mometazona furoat (monohydrate) - synthetic adrenokortikoid for dermatological! Application that possesses anti-inflammatory action and high local activity. Well Pozakonazol - antifungal broad-spectrum agent from group of triazole gets through the uninjured skin. Fungicide effect pozakonazol Enzyme lanosterin-14-demetilazy (CYP51) is based on selective inhibition that participates in biosynthesis of an ergosterol at yeast and filamentous mushrooms. Kak showed the researches in vitro, pozakonazol has fungicide activity against about 7000 strains of yeast and filamentous mushrooms (in particular, Malasseziapachydermatis). On the power of fungicide action Malassezia pachydermatis in vitro is relative, pozakonazol was 40-100 times more effective, than klotrimazol, mikonazol and nystatin Absorption of medicine happens generally during the first several days after putting medicine on skin. Extent of skin absorption depends on a condition of an epithelial barrier. Vospaleniye promotes skin absorption of medicines of local action Application: Treatment of the dogs sick with the sharp and chronic external otitises caused by microorganisms to an orbifloksatsin and to mushrooms, sensitive to a pozakonazol (for example, Malassesia pachydermatis) the Dosage: Only for external application - instillation in an ear. One drop contains 244 mkg of an orbifloksatsin, 24 mkg of a mometazon furoat and 24 mkg of a pozakonazol the External ear have to be clean and dry. From it it is necessary to remove dirt, surplus of hair, foreign materials, crusts, exudate and t.p it is good to be afraid before burying to Dogs with a body weight up to 2 kg dig in 2 drops in an ear of 1 times a day to Dogs with a body weight from 2 to 15 kg dig in 4 drops in an ear of 1 times a day to Dogs with a body weight more than 15 kg dig in 8 drops in an ear of 1 times a day to Dig in medicine of room temperature Process once a day. Dlitelnost treatments of 7 days After burying carefully mass an auricle basis for the best distribution of medicine after ear canals of Protivopokazaniya: To apply Ne to dogs with perforation of an eardrum. Ne to apply hypersensibility pp to any components of medicine of Ne to apply along with medicines that have ototoksichny action Caution: To apply Ne ПОЗАТЕКС® during pregnancy and to mix Nes lactations with other veterinary medicines and substances Bacterial and fungal otitises, as a rule, diseases of the secondary nature. Dl of successful treatment it is necessary to diagnose and control the main disease Constant application of the same class of antibiotics can lead to emergence of resistant forms of microorganisms. It is undesirable to use ftorkhinolona as a "reserve" antibiotic for treatment of patients, with the absent / insufficient positive reaction to other medicines Because of threat erosive damage of an articulate cartilage and other forms of artropatiya at young animals, ftorkhinolona do not apply an animal, is younger than 4-month age Prolonged use of corticosteroids of local action in high doses can lead to such system and local phenomena: oppression of function of adrenal glands, thinning of epidermis and a delay of healing of wounds and t.p Before introduction of medicine to an ear canal it is necessary to be convinced of integrity of an eardrum to avoid entering of an infection in a middle ear and to protect cochlear and vestibular devices from prolongation of contact with medicine Storage components: The place, dry, dark, inaccessible for children, at a temperature from 2 ˚ to 25 s the Producer: Intervet International B.V., the Netherlands Is made: Vet Pharma Friesoythe GmbH, Germany Product code: 126528 - Msd Animal Heals of Pozatex of a drop ear, suspension for the sobakdat editing the description: 07.12.2020