tablets "Lomfloks" are applied at indications which are provided below.

Lomefloksatsin intends for treatment of adults at the infectious and inflammatory diseases caused by microorganisms, sensitive to a lomefloksatsin, from easy to a moderate infection in cases:

• a lower respiratory tract infection;

Bacterial exacerbation of chronic bronchitis caused by Haemophilus influenzae or Moraxella catarrhalis activators. Lomefloksatsin is not appointed for imperichesky treatment at bacterial exacerbations of chronic bronchitis if there is a probability that Streptococcus Pneumoniae is the activator.

• an infection of urinary tract;

At uncomplicated (including recuring) urinary tract infections (cystitis, pyelonephritis, prostatitis, an urethritis) of the caused Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, or Staphylococcus saprophyticus.

At the complicated infections activators Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Citrobacter diversus, or Enterobacter cloacae.

It was established ​​ safety and efficiency of a lomefloksatsin at treatment of patients at pyocyanic bacteremia.

• preoperative and after operational prevention of infectious and inflammatory diseases of infections of an urinary system at transurethral interventions (including at adenectomy, a remote lithotripsy) and a transrectal biopsy of a prostate;

Early and late postoperative periods (from 3rd to 5 days and from 3rd to 4 weeks after operation).

Transurethral surgical procedures: for reduction of cases of an infection of urinary tract during the early postoperative period (3-5 days after operation).

• sharp and chronic gonorrhea;
• sharp and recurrent clamidiosis (including the mixed bacterial chlamydial infection);
• sharp and persistent purulent infections of leather and soft tissues, contaminated wounds.

Structure

Active ingredient - lomefloxacin (one tablet supports a lomefloksatsin of a hydrochloride it is equivalent to a lomefloksatsin of 400 mg).

Excipients: waterless lactose, starch corn, povidone, sodium krakhmalglikolit (type A), krospovidon, talc, sodium lauryl sulfate, magnesium stearate, propylene glycol, silicon dioxide colloidal waterless, a gipromelloza, the titan dioxide (E 171).

Contraindication

Hypersensitivity to a lomefloksatsin and to other hinolona (derivatives of quinoline carboxylic acid) and other components of medicine; epilepsy; injuries of the central nervous system (CNS) with the lowered convulsive threshold (in particular, after a craniocereberal trauma, a stroke or inflammatory processes in central nervous system) in the anamnesis.

to Apply

inside (without chewing, washing down with water) to or after a meal. The dose of medicine and duration of treatment depend on a look, severity of an infection and clinical performance of the performed therapy and in general makes one tablet (400 mg) of 1 times a day and does not exceed 7-10 days. In particular the following types and severity of an infection are allocated:

• at uncomplicated infections of urinary tract - 400 mg of 1 times a day within 3-5 days;
• at the uncomplicated cystitis caused by Klebsiella pneumoniae, Proteus mirabilis, or Staphylococcus saprophyticus - 400 mg of 1 times a day within 10 days;
• at uncomplicated cystitis at women which is caused by Escherichia coli - 400 mg of 1 times a day within 3 days;
• at the complicated infections of urinary tract - 400 mg of 1 times a day within 10-14 days;
• prevention of infectious and inflammatory diseases of urinary tract at transurethral operations - 400 mg once, in 2-6 hours prior to operation;
• at sharp gonorrhoeas - 600 mg once, at chronic gonorrhea - 600 mg a day within 5 days against the background of a specific immunotherapy;
• at urogenital clamidiosis, including the mixed bacterial chlamydial infection, including gonorrheal and chlamydial to accept on 400-600 mg of 1 times a day up to 28 days;
• a chlamydial infection at patients with rheumatism - 400 mg a day within 20 days; chlamydial conjunctivitis - 400 mg a day, a course of treatment - up to 10 days;
• a mycoplasmal infection - 400-800 mg a day, a course of treatment - up to 10 days;
• at sharp and persistent purulent infections of soft tissues, treatment of contaminated wounds and burns - 400 mg of 1 times a day within 5-14 days;
• chronic osteomyelitis - 400-800 mg a day, a course of treatment - from 3rd to 8 weeks;
• at uncomplicated bronchitis and pneumonia - 400 mg of 1 times a day up to 10 days;
• at the complicated infections of lower parts of airways, including pneumococcal pneumonia, exacerbation of chronic bronchitis - 400-800 mg 1-2 times a day within 14 days;
• at sharp bacterial exacerbation of chronic bronchitis - 400 mg of 1 times a day within 10 days;
• at tuberculosis to take the medicament on 400 mg 2 times a day 14-28 days and longer;
• at a transrectal biopsy of a prostate - 400 mg once in 1-6 hours prior to the procedure.

to

Pregnant

Drug is contraindicated to

Feature of application

for treatment feeding by a breast should be stopped.

Drug not to appoint

to children.

Drivers

to Patients during treatment is recommended to abstain from control of motor transport or work with the mechanisms demanding the increased concentration of attention and speed of psychomotor reactions.

Overdose

strengthening of side effects (tremor, a loss of consciousness, hypersalivation, nausea, vomiting, decrease of the activity, short wind, spasms). At accidental and/or conscious overdose it is necessary to clean a stomach, having caused vomiting and/or by washing, to provide sufficient hydration of an organism. If necessary carry out symptomatic therapy. The hemodialysis and peritoneal dialysis are inefficient.

Side effects

General frustration: the increased perspiration, inflows, weakness, increased fatigue, reduced shipping of high temperature, a dorsodynia, an adynamy, a face edema, a fever, grippopodobny symptoms, tendency to respiratory infections, joint pains, sinews and muscles.

At prolonged use side reactions which are provided below can arise.

from a digestive tract: an abdominal pain, heartburn, dryness in a mouth, thirst, lack of appetite, increase in appetite, nausea, vomiting, diarrhea, dyspepsia, a meteorism, a lock, gastrointestinal bleedings, inflammations of digestive tract, a dysphagy, stomatitis, discoloration of language, change of taste, pseudomembranous colitis.

from organs of hearing: ear pain, ring in ears.

from nervous system: a headache, dizziness, loss and confusion of consciousness, agitation, uneasiness, sleep disorders, insomnia, drowsiness, psychocontagious excitation, hallucinations, an incoordination of movements, a depression, depersonalization, paranoid reactions, violation of thinking, violation of concentration of attention, a fever, a tremor, paresthesias, twitching of muscles, spasms in muscles, hyperkinesias, cerebrovascular frustration, an ataxy, a coma, a hypertension.

Reaction of hypersensitivity: skin reactions in the form of rash, a small tortoiseshell, an itch.

from the haematogenic and lymphatic system: purple, lymphadenopathy, increase in a fibrinolysis.

Metabolism, metabolism: hyperglycemia, hypoglycemia, hypopotassemia, gout.

from an organ of sight: disorder of vision, diplopia, conjunctivitis, photophobia, eye pain, dacryagogue.

from a reproductive system and mammary glands: women have a vaginal candidiasis, a vaginitis, a leukorrhea, violations of a menstrual cycle, crotch pain, intermenstrual bleedings, men have an epididymite, an orchitis.

Infection and invasion: viral infections, thrush, fungal infection.

from a respiratory system: rhinitis, pharyngitis, short wind, cough, nasal bleeding, bronchospasm, disorders of breath, increase in expectoration, bronchospasm, stridor, respiratory depression, thorax pain, embolism of a pulmonary artery.

from a musculoskeletal system: arthralgia, tendinitis.

from the immune system: anaphylactoid reactions, acute anaphylaxis, Quincke's disease.

from skin and hypodermic cellulose: exfoliative skin changes, various rashes, eczema, acne, skin discoloration, Stephens-Johnson's syndrome, toxic epidermal necrolysis, skin ulcers, hyperpegmentation.

to Store

in original packing at a temperature not above 25 °C, out of children's reach.

Expiration date - 3 years.