Structure and form of release

Structure

Active ingredient: Bifidobacterium animalis subsp. lactis;

1000000000 WHICH Bifidobacterium animalis subsp. lactis;

Excipients: maltodextrin.

a release Form

Powder for oral suspension.

Pharmacological properties

Pharmakodinamichesky parameters. bifidobacteria — a component of a normal intestinal microbiota of the person — some of the first colonize a digestive tract of the newborn, are the dominating colibacilli at the children who are on breastfeeding and are necessary for development of the child at early age.

Tyre-tread and medical action of Bifidobacterium animalis subsp. by lactis which contain in Linex ^® baby it is carried out in several ways: the specified strain limits growth in a GIT of causative organisms at the expense of an obstacle of their adhesion to an intestinal wall and further colonization and also by competitive antagonism for food substrates, creations of low values rn in an intestines gleam thanks to products of acids, production of peroxide of hydrogen and the bacteriocines having antimicrobic properties. Besides, Bifidobacterium animalis subsp. lactis activates the immune response.

Disorder of physiological balance of an intestinal microbiota owing to influence of activators of the virus or bacterial nature, infections of a digestive tract, antibiotiko- and chemotherapy, delay of configuration of normal structure of an intestinal microbiota in the period of a neonatality causes dispeptic disorders — emergence of the increased gas generation in intestines, gripes, defecation disturbances and also development of atopic dermatitis.

Thanks to systematic use of Bifidobacterium animalis subsp. lactis is effective the expressiveness and frequency of manifestations of the gastrointestinal disorders (diarrheas first of all) which resulted from an intestinal disbioz decreases; conditions for normal intestinal activity are created. Linex ® baby is used by ^{for prevention or as a component of complex treatment of atopic dermatitis, or for the purpose of normalization of activity of the intestinal immune system.}

Pharmacokinetic parameters. After introduction of Bifidobacterium animalis subsp. lactis cause local effect in a digestive tract. Studying pharmacokinetic parameters was not carried out as absorption in a system blood stream does not happen. Resistance of a strain to influence of gastric juice and bile provides high survival of Bifidobacterium animalis subsp. lactis when passing through upper parts of a GIT. Representatives of this strain form steady coupling with intestinal slime and owing to peristaltic reductions and the act of defecation are slowly excreted from an organism.

Indication

At children aged from the 1st day of life to 12 years:

• for normalization and maintenance of activity and balance of an intestinal microbiota;
• for prevention and as the supporting means in case of a meteorism, diarrhea or other infectious pathology of a digestive tract of a virus or bacterial etiology (including caused by a rotavirus);
• against the background of antimicrobic therapy.

Use

to Children — 1 package during meal. frequency rate of reception: aged from the 1st day of life to 2 years — 1 times a day; at the age of 2–12 years — 1–2 times a day.

with baby food or liquid (milk, juice, water).

Cannot accept Linex of ^® baby with the drinks heated to high temperature.

Course of use Linex ^® baby can proceed before disappearance of corresponding manifestations of a disease.

Contraindication

Hypersensitivity to active pharmaceutical ingredient or maltodextrin.

Side effects

In rare episodes hypersensitivity reactions — an itching, rashes.

Special instructions

in case of fever it is above 38 °C, diarrhea duration more than 2 days, of the profound diarrhea with eksikozy and degrowth of a body, emergence of slime or blood in a chair, intensive abdominal pain, in the presence at the child of chronic pathology, such as cardiovascular diseases or diabetes, immunodeficiency (for example HIV infection) before use of medicament it is necessary to see a doctor for consultation.

therapy of diarrhea has to take place under medical control.

At therapy of diarrhea.

In view of lack of the corresponding researches information on impact on speed of response at control of vehicles or other mechanisms.

Interaction

it is not established.

Because of sensitivity of bifidobacteria to antibiotics reception of Linex of ^® baby should be carried out later 3 h after use of the specified means.

Overdose

it is not revealed.

Storage conditions

At a temperature of ≤25 °C in original packing in the place inaccessible for children.