Solution for infusions Levofloxacin is appointed the adult for treatment of the infections caused by microorganisms, sensitive to a levofloksatsin:

• not hospital pneumonia;
• complicated infections of leather and soft tissues;
• sharp pyelonephritis, the complicated infections of urinary tract;
• chronic bacterial prostatitis.

Structure

Active ingredient: levofloxacin;

100 ml of solution the levofloksatsina of the gemigidrat in terms of waterless 100% contains levofloxacin of 500 mg;

Excipients: sodium chloride, dinatrium edetat, divorced Acidum hydrochloricum, sodium hydroxide, water for injections.

Contraindication

Hypersensitivity to a levofloksatsin or to other hinolona, epilepsy, side reactions from sinews after preliminary application of hinolon. Children's age (up to 18 years). Period of pregnancy or feeding by a breast.

Route of administration

Before use of medicine sensitivity test. To use medicament for intravenous administration for 3 hours after perforation of a rubber bung. Protection against light at infusion is not necessary. At room lighting it is possible to store solution for intravenous administration not longer than 3 days without protection against light.

to administer the Drug slowly 1 or 2 times a day. The dosage depends on type and weight of an infection and also sensitivity to medicament of the possible activator.

Pregnant

Drug is contraindicated to

Feature of application

Children

Use of medicine is contraindicated to children (age up to 18 years) as injury of an articulate cartilage is not excluded.

Drivers

with machines and mechanisms, it is necessary to consider possible undesirable reactions from nervous system (dizziness, drowsiness, confusion of consciousness, a disorder of vision and hearing, violation of processes of the movement, including also during walking).

Overdose

Most important expected symptoms of overdose touch the central nervous system (dizziness, violation of consciousness and convulsive attacks); reactions from a GIT, such as nausea and erosion of mucous membranes. At application of the doses exceeding therapeutic there is a lengthening of a QT interval. In case of overdose it is necessary to make careful observation of the patient, including the ECG.

Side effects

• Infection and invasion. Infrequently: fungal infections, including the infection caused by sort Candida fungi. Resistance of pathogenic microorganisms.
• from mentality. Often: insomnia. Infrequently: uneasiness, confusion of consciousness, nervousness.
• from nervous system. Often: headache, dizziness.
• from the vascular system. Often: phlebitis (only for intravenous forms of introduction).
• from a liver and bile-excreting channels. Often: increase in activity of liver enzymes (ALT/nuclear heating plant, alkaline phosphatase, GGT).
• General violations and reactions in the injection site. Often: reaction in the place of infusion (pain, reddening).

Interaction

In researches of clinical pharmacology was shown that on pharmacokinetics of a levofloksatsin was not caused any clinically significant influence at application of a levofloksatsin together with the following medicines: calcium carbonate, digoxin, glibenclamide, ranitidine.

to Store

at a temperature not above 25 °C in protected from light and the place, inaccessible for children.

Expiration date - 3 years.