tablets Levofloxacin are shown for treatment of the infections caused by microorganisms, sensitive to a levofloksatsin:

• sharp bacterial sinusitis;
• exacerbation of chronic bronchitis;
• community-acquired pneumonia;
• complicated infections of leather and soft tissues (in case of treatment of above-mentioned infections, medicament is used only when use of other antibacterial agents which usually appoint for initial treatment of these infections is impossible);
• complicated infections of urinary tract (including pyelonephritis);
• chronic bacterial prostatitis;
• uncomplicated cystitis;
• inhalation anthrax: post-contact prevention and treatment.

Structure

Active ingredient: 1 tablet contains 256.23 mg of a levofloksatsin of the gemigidrat that is equivalent to 250 mg to a levofloksatsin;

1 tablet contains 512.46 mg of a levofloksatsin of the gemigidrat that is equivalent to 500 mg of a levofloksatsin;

Excipients: a gipromelloza, krospovidon, cellulose microcrystalline, the sodium stearylfumarating polyethyleneglycol 6000, talc, ferrous oxide red (E172), ferrous oxide yellow (E172), the titan dioxide (E 171).

Contraindication

• hypersensitivity to a levofloksatsin, other ftorkhinolona or to any component of medicine;
• epilepsy;
• injury of a sinew connected with the previous application of ftorkhinolon;
• children's age;
• period of pregnancy and feeding by a breast.

by

for oral administration. It is necessary to swallow of tablets without chewing, washing down with enough liquid. It is possible to take the medicament irrespective of meal.

should use Drug not less than in 2 hours prior to or after use of salts of iron, salts of zinc, the antacids containing magnesium or aluminum, a didanozina (only for the forms containing aluminum or magnesium in buffer means) and the sukralfat.

to

Feature of application

Pregnant

It is contraindicated.

Children

It is contraindicated.

Drivers

With care.

Overdose

Symptoms: violations from the central nervous system (confusion of consciousness, dizziness, violation of consciousness and convulsive attacks, hallucinations and a tremor) of violation from digestive system (nausea and an erosion of mucous membranes) the lengthening of a QT interval is possible.

Treatment: symptomatic therapy. It is necessary to carry out monitoring of the ECG as prolongation of an interval of QT is possible. Mucous a stomach apply antiacid means to protection. The hemodialysis, including peritoneal dialysis or HAPD, is not effective for removal of a levofloksatsin from an organism. There is no specific antidote.

Side effects

from mentality: often (from> 1/100 to <1/10) - insomnia.

from nervous system: often (from> 1/100 to <1/10) - a headache, dizziness.

from digestive tract: often (from> 1/100 to <1/10) - diarrhea, nausea, vomiting.

from a gepatobiliarny system: often (from> 1/100 to <1/10) - increase in activity of liver enzymes (ALT/nuclear heating plant, alkaline a phosphobasin, GGTP).

Interaction

In researches of clinical pharmacology was shown that on pharmacokinetics of a levofloksatsin was not caused any clinically significant influence at application of a levofloksatsin together with the following medicines: calcium carbonate, digoxin, glibenclamide, ranitidine.

to Store

at a temperature not above 30 °C.

to Store

out of children's reach.

Expiration date - 3 years.