Pharmacological properties

Pharmacodynamics. interferon alpha 2b recombinant the person — high cleaning soluble protein in water with a molecular weight of 19,300 yes.

Laferon-FarmBiotek Nazalny has direct antiviral effect. Under the influence of interferon the reproduction of viruses stops (flu, a parainfluenza, adenoviruses, rhinoviruses, reoviruses, etc. in the infected cages and also the protective factors warning infection of other cages are developed. Additional immunomodulatory effect of medicine consists in activation of phagocytosis, stimulation of antibody formation and lymphokines.

Pharmacokinetics. It was not studied.

Indication

Laferon-pharmbiotek nasal is applied for:

• treatment and prevention of a SARS and virus and bacterial infections at adults and children, including newborns;
• for the purpose of prevention at threat of a disease (during the epidemic period, at contact with the patient of a SARS);
• in complex therapy of viral diseases of eyes, various forms of an oftalmogerpes (the keratoconjunctivitis, keratouveit).

Use

With the medical purpose medicament should be used as soon as possible — at the first symptoms of a disease. the efficiency of medicine of subjects is higher, than its application is begun earlier.

Bottle with dry powder of medicine to open and fill with the boiled water cooled to the room temperature (15–25 °C) (for intranasal application) or physiological solution of sodium of chloride (0.9%) (for preparation of eye drops).

For preparation of nasal and eye drops to a bottle 5 ml of the corresponding solvent. It is dense to close a bottle a cover dropper which is applied and to swing carefully before full dissolution of powder. Drops are ready to use. After each use of medicine to close a dropper a protective cap. 1 ml of the prepared solution contains about 200 thousand ME of interferon.

For treatment of flu and other respiratory viral infections of a drop Laferon-FarmBiotek Nazalny is dug in in each nasal course in the following doses:

— to babies, including premature — on 1 drop of 4-5 times a day;

— to children aged from 1 year up to 7 years — on 2–3 drops of 4-5 times a day;

— to children 7 years are aged more senior — on 2–3 drops of 5-6 times a day;

— the adult — on 4–5 drops of 6-8 times a day.

Usually the course of the antiviral Laferon-FarmBiotek Nazalny medicament treatment makes 3–5 days.

for the purpose of prevention at contact with the patient and when overcooling Laferon-FarmBiotek Nazalny are applied according to an age dosage by 2 times a day within 5–7 days. If necessary preventive courses are repeated. At single contact of rather single application. At seasonal increase in incidence — once in the morning with an interval of 1-2 days

In complex therapy of viral diseases of eyes, various forms of an oftalmogerpes (the keratoconjunctivitis, keratouveit) Laferon-FarmBiotek Nazalny solution — 1 million ME in 5 ml of physiological solution — dig in in a conjunctival sac of the affected eye on 2–3 drops in each 2 h within 7–10 days, after disappearance of symptoms of a disease medicament can be used in each 4 h

Contraindication

Individual intolerance of interferon alpha 2b and other components which are a part of medicine, severe forms of allergic diseases in the anamnesis. period of pregnancy and feeding by a breast.

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Special instructions

for the purpose of maintaining biological activity of medicine for dissolution of powder should use only the liquid cooled to the room temperature (15–25 °C).

For intranasal introduction use the boiled water cooled to room temperature as solvent.

For instillation medicine in a conjunctival sac of the affected eye as solvent use physiological solution of sodium of chloride (0.9%).

Children. Laferon-FarmBiotek Nazalny apply in pediatric practice, including to newborn and premature children. To children of a drop apply under observation of adults.

Use during pregnancy and feeding by a breast. There are not enough data on use of medicine during pregnancy and feeding by a breast. Use is contraindicated.

Ability to influence speed of response at control of vehicles or work with other mechanisms. It was not investigated.

Interaction

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Overdose

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Storage conditions

In original packing at a temperature from 2 to 8 °C. to store out of children's reach.

After opening of a bottle and preparation of solution within 5 days in the fridge or 2 days at the room temperature (15–25 °C). To protect the prepared solution from actions of direct sunshine.