Laferobion - antiviral, antimicrobic, anti-inflammatory and immunomodulator. Immunostimulator. Interferon alpha 2б for prevention and treatment of the acute respiratory viral infections (ARVI):

• at patients, it is frequent and long the upper airways having diseases;
• at contact with sick SARS;
• when overcooling;
• at seasonal increase in incidence.

Structure

• active ingredient: interferon alfa-2b;
• 1 ml of medicine supports interferon alpha 2b the recombinant person of 100,000 ME;
• excipients: trometamol, to a trometamol a hydrochloride, a gipromelloza, sodium edetat, a lysine a hydrochloride, potassium chloride, methylparahydroxybenzoate (E 218), water for injections.

Contraindication

Hypersensitivity to interferon alpha 2b and other components which are a part of medicine, severe forms of allergic diseases in the anamnesis dysfunction of a thyroid gland; presence of heavy visceral violations at patients with Kaposi sarcoma; serious cardiovascular illness; psoriasis, the expressed abnormal liver functions and/or kidneys; epilepsy and other diseases of the central nervous system (including functional); chronic hepatitis against the background of the progressing or dekompensirovanny cirrhosis; chronic hepatitis at the patients receiving or recently autoimmune hepatitis or other autoimmune diseases in the anamnesis received therapy by immunodepressants (except a short course of corticosteroids). Oppression of a myeloid sprout of blood formation. Pregnancy and period of feeding by a breast.

Route of administration

Drug is administered in each nasal course.

1 spray dose = 1 short pressing the doser.

Scheme of use of spray nasal:

1. to Remove a protective cap from a bottle.
2. to Activate microdosers sprays pressing (trial dispersion).
3. Being in vertical position, to place the end of a nozzle in the nasal course and to press the pump doser. To repeat input in other nasal course.
4. After application to close a bottle a cap.

At the first symptoms of a disease of a SARS (within 5 days)

Adult - on the 3rd spray dose in each nasal course of 5-6 times a day (a single dose - 30,000 ME, a daily dose - 150 000 - 180 000 ME).

Children. To children aged from 1 up to 3 years - on the 2nd spray dose in each nasal course 3-4 times a day (a single dose - 20,000 ME, a daily dose - 60 000 - 80 000 ME).

to Children aged from 3 up to 14 years - on the 2nd spray dose in each nasal course of 4-5 times a day (a single dose - 20,000 ME, a daily dose - 80 000 - 100 000 ME).

to Children aged from 14 up to 18 years - on the 3rd spray dose in each nasal course of 5-6 times a day (a single dose - 30,000 ME, a daily dose - 150 000 - 180 000 ME).

For prevention of respiratory viral infections at adults

At contact with the patient and when overcooling - on the 3rd spray dose 2 times a day within 5-7 days. If necessary preventive courses are repeated. At single contact of rather single application.

At seasonal increase in incidence - once in the morning with an interval of 1-2 days.

Feature of application

Drug contains methylparahydroxybenzoate which can cause the allergic reactions including delayed in exceptional cases - a bronchospasm.

should not use medicament at violation of integrity and marking of packing, at change of physical properties (color or transparency of liquid) and after expiry date.

in order to avoid spread of an infection, recommends individual use of a bottle.

Use is contraindicated to

.

Children

to Apply

to children aged from 1 year at the first symptoms of a disease of a SARS.

Ability to influence speed of response at control of motor transport or other mechanisms

does not influence.

Overdose

Data on overdose of medicine.

Side reactions

General violations: often - a dose-dependent grippopodobny syndrome (fever, fervescence, head and muscular pain, a joint pain, feeling of fatigue, slackness, perspiration) it is rare - nausea, vomiting, dizziness, inflows. Disturbance of electrolytic balance. Emergence of reactions of hypersensitivity to medicine, including an acute anaphylaxis, a Quincke's edema is possible.

from skin and hypodermic cellulose: rash on skin (in rare instances), including herpetic, an itch, hyperaemia, a cutaneous dropsy, urticaria, xeroderma, an alopecia.

from an endocrine system: dysfunction of a thyroid gland.

from an organ of sight: disorder of vision, conjunctiva hyperaemia.

from a digestive tract: loss of appetite, increase in level of alaninaminotranspherase, aspartate aminotransferase, alkaline phosphatase.

from digestive system: abnormal liver function.

to Store

in original packing for protection against effect of light at a temperature from 2 to 8 °C.

to Store

out of children's reach.

Expiration date 2 years. An expiration date after opening of a bottle, on condition of storage at a temperature from 2 to 8ºС - 10 days.