Laferobion - antiviral, antimicrobic, anti-inflammatory and immunomodulator. Interferona. Interferon alpha 2б for prevention and treatment of the acute respiratory viral infections (ARVI):

• at patients, it is frequent and long the upper airways having diseases;
• at contact with sick SARS;
• when overcooling;
• at seasonal increase in incidence.

Structure

• active ingredient: interferon alfa-2b;
• 1 ml of medicine supports interferon alpha 2b the recombinant person of 100,000 ME;
• excipients: trometamol, to a trometamol a hydrochloride, a gipromelloza, sodium edetat, a lysine a hydrochloride, potassium chloride, methylparahydroxybenzoate (E 218), water for injections.

Contraindication

Hypersensitivity to interferon alpha 2b and other components which are a part of medicine, severe forms of allergic diseases in the anamnesis dysfunction of a thyroid gland; presence of heavy visceral violations at patients with Kaposi sarcoma; serious cardiovascular illness; psoriasis, the expressed abnormal liver functions and/or kidneys; epilepsy and other diseases of the central nervous system (including functional); chronic hepatitis against the background of the progressing or dekompensirovanny cirrhosis; chronic hepatitis at the patients receiving or recently autoimmune hepatitis or other autoimmune diseases in the anamnesis received therapy by immunodepressants (except a short course of corticosteroids). Oppression of a myeloid sprout of blood formation. Pregnancy and period of feeding by a breast.

Route of administration

Drug is administered in each nasal course.

Before use of medicine needs to accept a dorsal decubitus or sitting, to reject slightly the head back and to turn towards that nasal course to which it will be carried out burying drops. Without affecting by a dropper of a bottle of internal walls of a nose, to dig medicine. Right after burying for hypodispersion of medicine on a mucous membrane of a nose it is recommended to massage from the outside fingers nose wings within several minutes.

At the first symptoms of a disease of a SARS (within 5 days)

Adult - on 3 drops in each nasal course of 5-6 times a day (a single dose - 24,000 ME, a daily dose - 120 000 - 144 000 ME).

Children. To newborns and children till 1 year - on 1 drop in each nasal course of 5 times a day (a single dose - 8000 ME, a daily dose - 40,000 ME).

to Children aged from 1 up to 3 years - on 2 drops in each nasal course 3-4 times a day (a single dose - 16,000 ME, a daily dose - 48 000 - 64 000 ME).

to Children aged from 3 up to 14 years - on 2 drops in each nasal course of 4-5 times a day (a single dose - 16,000 ME, a daily dose - 64 000 - 80 000 ME).

to Children aged from 14 up to 18 years - on 3 drops in each nasal course of 5-6 times a day (a single dose - 24,000 ME, a daily dose - 120 000 - 144 000 ME).

For prevention of respiratory viral infections at adults

At contact with the patient and when overcooling - on 3 drops 2 times a day within 5-7 days. If necessary preventive courses are repeated. At single contact of rather single application.

At seasonal increase in incidence - once in the morning with an interval of 1-2 days.

Scheme of use of drops nasal in a bottle, corked Mikrodozatory-kapelnitsey:

1. to Remove a protective cap from a bottle.
to return to
2. Before the first application of drops a bottle a nozzle down and to make several trial pressing the pump doser.
3. to Place the end of a nozzle serially in each nasal course and to press the pump doser necessary number of times according to a dosage.
4. After application to close a bottle a cap.

Feature of application

in order to avoid spread of an infection, recommends individual use of a bottle.

hits of medicine on a mucous membrane of eyes.

Use is contraindicated to

.

Children

apply Medicine to children since the birth at the first symptoms of a disease of a SARS.

Ability to influence speed of response at control of motor transport or other mechanisms

does not influence.

Overdose

Data on overdose of medicine.

Side reactions

General violations: often - a dose-dependent grippopodobny syndrome (fever, fervescence, head and muscular pain, a joint pain, feeling of fatigue, slackness, perspiration) it is rare - nausea, vomiting, dizziness, inflows. Disturbance of electrolytic balance. Emergence of reactions of hypersensitivity to medicine, including an acute anaphylaxis, a Quincke's edema is possible.

from skin and hypodermic cellulose: rash on skin (in rare instances), including herpetic, an itch, hyperaemia, a cutaneous dropsy, urticaria, xeroderma, an alopecia.

from an endocrine system: dysfunction of a thyroid gland.

from an organ of sight: disorder of vision, conjunctiva hyperaemia.

from a digestive tract: loss of appetite, increase in level of alaninaminotranspherase, aspartate aminotransferase, alkaline phosphatase.

from digestive system: abnormal liver function.

from an urinary system: renal failure.

from the system of blood and lymphatic system: leukopenia, thrombocytopenia, anemia, nasal bleedings.

from a cardiovascular system: arterial hypertension and hypotension, tachycardia.

from nervous system: dizziness, sleep disorder, ataxy, paresthesias, confusion of consciousness, alarming and depressions, hyperexcitability, drowsiness.

from the respiratory system, bodies of a thorax and mediastinum: cough, short wind.

in case of undesirable reactions should consult with the doctor.

to Store

in original packing for protection against effect of light at a temperature from 2 to 8 °C.

Expiration date 2 years. An expiration date after opening of a bottle, on condition of storage at a temperature from 2 to 8 °C - 10 days.