Tablets "Kardosal ^® 40 mg" are applied at the following indications:

• treatment of essential arterial hypertension at adult patients;
• treatment of arterial hypertension at children and teenagers aged from 6 up to 18 years.

Structure

Active ingredient - olmesartan medoxomil (one tablet, coated, contains 40 mg of an olmezartan of a medoksomil).

Excipients: cellulose microcrystalline, the hydroxypropyl cellulose low-substituted, lactoses monohydrate, hydroxypropyl cellulose, magnesium stearate, the titan dioxide (E 171), talc, a gipromelloza.

Contraindication

• hypersensitivity to active ingredient or to one of medicament components;
• pregnant women or women who are going to become pregnant;
• obstruction of biliary tract;
simultaneous use of an olmezartan medoksomit
• with medicaments which contain aliskiren, it is contraindicated to patients, sick diabetes and a renal failure (SKF <60 ml/minute / 1.73 m ² ).

Route of administration

Adult

Initial daily dose of an olmesartan of a medoksomil makes 10 mg of 1 times a day. If a lowering of arterial pressure insufficient, then a dose it is necessary to increase to 20 mg of 1 times a day. If there is a need, it is possible to increase a dose to 40 mg of 1 times a day (maximum daily dose) or to add a hydrochlorothiazide to treatment.

Antihypertensive effect of an olmezartan of a medoksomil is observed by

, as a rule, within 2 weeks after an initiation of treatment, and the maximum effect is observed in 8 weeks after the beginning of therapy. It should be meant by consideration of change of the mode of dosing for any patient.

for the purpose of observance of the mode of dosing medicament is recommended to be used approximately at the same time every day, with or without food, for example, during a breakfast. Tablets should be washed down with enough liquid. The tablet should not be chewed.

Children and teenagers aged from 6 up to 18 years

Recommended initial dose of an olmezartan medoksomit

to children aged from 6 up to 18 years makes 10 mg of 1 times a day. If arterial blood pressure does not decrease sufficiently, the dose can be raised to 20 mg of 1 times a day. In need of more profound lowering of arterial pressure, children with body weight ≥ 35 kg can raise a dose of an olmezartan of a medoksomil to 40 mg a day. For children with body weight <35 kg the daily dose should not exceed 20 mg.

to

Pregnant

to

Medicine is contraindicated to

Feature of use

pregnant women or women who are going to become pregnant. If during treatment the pregnancy is confirmed by medicine, its use needs to be stopped and replaced immediately with other medicine allowed for use for pregnant women.

to Women who nurse should not use medicament due to the lack of experience of its use during this period. Instead of it it is possible to use other antihypertensive medicaments which safety of use during feeding by a breast is proved, especially when feeding babies or premature children.

Drivers

Drug has insignificant or moderate influence on ability to run vehicles or other mechanisms. Dizziness or increased fatigue can sometimes arise at the patients accepting antihypertensive therapy that can break ability to reaction.

Overdose

About overdose is only limited information. The most probable effect at overdose is arterial hypotension. In case of overdose for the patient it is necessary to observe and carry out symptomatic, maintenance therapy attentively.

is not present

Data on a possibility of removal of an olmezartan of a medoksomil by dialysis.

Side effects

Side reactions most of which often arise during treatment by this medicine - headaches (7.7%), grippopodobny symptoms (4.0%) and dizziness (3.7%).

Storage conditions

Special storage conditions are not required for

. To store out of children's reach.

Expiration date - 3 years.