Intramitsin antibacterial veterinary medicine for system application produced in the form of homogeneous suspension, color from white to yellowish. It is applied in treatment of a number of diseases at cattle and also horses, sheep, pigs and pets - dogs and cats. The list of diseases includes the pneumonia, bronchitis, tracheitis, enteritis, cystitis, diarrhea, abscess, a metritis, mastitis, the postoperative infections infected wounds, etc., caused by the microorganisms sensitive to a benzilpenitsilin and dihydrostreptomycin.
Advantage of the medicine Intramitsin is the combination of two medicines - benzylpenicillin and dihydrostreptomycin - and their joint action enhancing effect of each of them separately.
Medicine well gets into lungs, kidneys, a liver, its concentration in blood is reached in 15-30 minutes and keeps till 8-12 oclock. Also undoubted advantage of this antibiotic it is necessary to call a number of diseases and a small course of treatment - only 3 days.
ATTENTION! Before application it is strongly recommended to study the instruction for use of medicine and to be given a medical prescription of veterinary medicine.
Instruction for use of the medicine Intramitsin: Description
Homogeneous suspension from white till yellowish color.
Structure
1 ml of medicine contains active ingredients:
benzylpenicillin (in the form of a prokain of monohydrate)-114 mg
dihydrostreptomycin (in the form of sulfate) - 200 mg.
Excipients: sodium methyl-parahydroxybenzoate, sodium hydroksimetansulfinat, a prokaina a hydrochloride, antifoam Silbione, sodium, 70% sorbitol, water for injections.
Pharmacological properties
ATC vet the classification QJ01-code antibacterial veterinary medicines for system application. J01RA01 is penicillin, combinations with other antimicrobial medicines.
Benzilpenitsillin is a bactericidal antibiotic of a penicillinic row. Benzilpenitsillin unites to a membrane of a bacterium and acts by oppression of the last stage of synthesis of a peptidoglikan.
Benzilpenitsillin affects with
gram-positive aerobic bacteria, including S. aureus, streptococci, especially beta and hemolytic, korinobakteriya, E. rhusiopathiae, Bacillus spp. and also the majority of Actonomyces spp. Some anaerobic bacteria, such as Clostridium spp. and some types of Bacteroides spp. (Not B. fragilis), are also sensitive.
Benzilpenitsillin acts with
on gram-negative aerobic bacteria, such as Pasteurella spp., Haemophylus spp., some types of Actinobacillus spp are less steady. that Leptospira spp., but it is not active against gram-negative bacilli.
Digidrostreptomitsin is a bactericidal antibiotic from group of aminoglycosides which influence synthesis of proteins and damage a cytoplasmatic membrane and also interfere with process of tissue respiration of mitochondrions of a cage. It bakteritsidno affects gram-negative and gram-positive microorganisms (Escherichia coli, Salmonella spp., Shigella spp., Yersinia spp., Klebsiella spp., Haemophilus influenzae, Staphylococcus spp., Corynebacterium pyogenes).
Complex medicine of benzylpenicillin and dihydrostreptomycin possesses a wide range of bactericidal action, and their combination - effect of synergism.
Prokain benzylpenicillin at intramuscularly introduction is well soaked up by
and quickly creates therapeutic concentration in blood in number of 1-2 mkg/ml - at horses, sheep, pigs, and 0.5 mkg/ml - at cattle, already through 2:00 after an injection. Medicine after introduction well gets into lungs, kidneys, a liver, badly gets into a myocardium, a brain, bones, synovial and cerebrospinal fluid. It is allocated from an organism in not changed look with kidneys (to 90%) and also with bile, saliva, milk.
bakteriostatichesky concentration of dihydrostreptomycin in blood is formed by
At parenteral introduction in 15-30 minutes and reaches a maximum in 1-2 hours. In therapeutic concentration (15 mkg/ml) the antibiotic contains in blood of 8-12 hours. It is removed generally by kidneys (95%).
Application
Treatment of the horses, cattle, sheep, goats, pigs, cats and dogs sick with pneumonia, bronchitis, tracheitis, enteritis, diarrhea, cystitis, a metritis, abscess, a wound infection, an infection of hoofs, mastitis, I will give birth to pigs, omfalit, at the postoperative infections caused by the microorganisms sensitive to penicillin and dihydrostreptomycin.
Dosage
Intramuscularly or hypodermically in doses:
cattle, horses are adult animal 5 ml of medicine on 100 kg of body weight once a day, young growth - 8 ml of medicine on 100 kg of body weight once a day;
sheep, a goat - 3-5 ml on an animal once a day;
pig - 1 ml of medicine on 10 kg of body weight once a day;
dog, a cat - 0.5 ml of medicine on 5 kg of body weight once a day.
Recommended course of treatment - 3 days.
Slaughter of animals on meat and consumption of milk in food is allowed to people by
respectively in 30 days and 3 days (or 6 sdaivaniye) after the last use of medicine. Received to the specified term, meat and milk utilize or feed an unproductive animal, depending on the conclusion of the doctor of veterinary medicine.
Storage
place, Dry, dark, inaccessible for children, at a temperature from 2 °C to 8 °C.
Expiration date - 2 years.
After the first selection from a bottle medicine needs to be used within 28 days on condition of storage in the dry dark place at a temperature from 2 °C to 8 °C.
For application in veterinary medicine!
Owner registration certificate :
Ceva Sante Animale, 10 avenue de la ballastière, 33500 Libourne, France
Packing : The glass or multilayered plastic bottles closed by rubber traffic jams under an aluminum running in on 50, 100 and 250 ml.
Producer : CEVA Sante Animale, Ceva Sante Animale, France
Species of an animal | Dogs Cats Horses |
Category of veterinary medicine | Antibiotics |
Area of application of veterinary medicine | skin Diseases Diseases of respiratory organs Gastrointestinal diseases Diseases of an urinogenital system |
Medicines | Chemotherapeutic medicines |
Form | Suspension |