FrontLine Combo (Frontline of the Combo) of the XL drop from 40 kg General provisions: Frontline of the Combo (Frontline Combo) - medicinal insektoakaritsidny medicine in the form of solution for external application Frontline of the Combo contains in quality of active ingredient fipronil-9.8% and S-metopren-of 8.8%, and as excipients - polividon and polysorbate Frontline of the Combo represents colourless transparent liquid, with a slight specific smell Release Frontline of the Combo packaged on 0.5; 0.67; 1.34; 2.68 and 4.02 ml in polyethylene pipettes with the breaking-off tip whom the name of the manufacturing organization is specified the name and amount of medicine, number of a series, date of production Store Frontline of the Combo precaution (list B) in packing of the producer, in the dry, protected from light place, at a temperature from 0C0 to 25C0. An expiration date of Frontline of the Combo, at observance of storage conditions – 3 years from the date of production. Frontline of the Combo should not be applied after an expiration date Pharmacological properties: Frontline of the Combo possesses the expressed contact insektoakaritsidny action, is active concerning preimaginalny and imaginal phases of development of the louses, fleas, vlasoyed and ticks (ixodic, heylitella) parasitizing on dogs and cats the Mechanism of action of the fipronil which is a part Frontline of the Combo consists in blocking GAMK-zavisimykh (GAMK-gammaaminomaslyanaya acid) receptors of parasites, violation of transfer of nervous impulses that leads to paralysis and death of ektoparazit of S-metopren are inhibited by the juvenile hormone promoting formation of chitin, breaking thereby, development of a flea at a stage of egg and a larva When drawing on skin medicine is not soaked up, and gradually, within 24 hours, being distributed on the surface of a body and, being reserved in sebaceous glands, has long insektoakaritsidny effect in places of localization of ektoparazit Frontline of the Combo on extent of impact on an organism belongs to low-dangerous substances (the 4th hazard class in accordance with GOST 12.1.007.76), in recommended doses, does not render the skin and resorptive, sensibilizing, embriotoksichesky, teratogenny and mutagen action. At hit in eyes the Order of use of vaccine causes weak irritation: Frontline of the Combo apply to fight against fleas, louses, vlasoyeda and pincers (ixodic, heylitellam) dogs and cats by topikalny (the Spot It) drawings on skin Before processing at the pipette break off a tip, move apart at an animal wool in a back (between shovels) and, pressing the pipette, apply medicine to skin in one or several points Depending on a look and the mass of an animal uses pipettes Frontline of the Combo of various volume: The weight of a dog the Volume of the used pipette (ml) the Number of pipettes up to 10 kg of 0.67 1 pieces from 10 to 20 kg of 1.34 1 pieces from 20 to 40 kg of 2.68 1 pieces more than 40 kg of 4.02 1 pieces of the Cat of 0.5 1 pieces of Dl of processing of dogs which weight more than 40 kg, use a combination of pipettes of different volume Protective effect of medicine against ixodic pincers at cats proceeds up to 3 weeks, against an imago and preimaginalny phases of development of insects up to 6 weeks the Protective effect of medicine against ixodic pincers at dogs continues not less than 1 month, against an imago of insects up to 3 months, from preimaginalny phases of development of insects – up to 8 months At strong defeat of an animal louses, fleas, vlasoyeda, it is recommended to make processing of Esli an animal once a month wash more often than 2 times a month it is recommended to reduce an interval between processings to 3 weeks Ne is recommended to wash animals within 48 hours after processing the Frontlayny Combo and also to use other insektoakaritsidny means of By-effects and complications at animals at application of Frontline of the Combo according to the instruction for application is not established. At the increased individual sensitivity to components of medicine and emergence of signs of allergic reactions the processing is stopped, medicine is washed away water, Side effects inside give antihistamines: In the recommended doses are not marked out Protivopokazaniya: Preparat Frontline It is not allowed to apply the Spot the sick and recovering animal, to puppies is younger than 10 weeks age and to dogs weighing less than 2 kg. Ne is recommended to wash animals within 48 hours after processing the Frontlayny Combo and also to use other insektoakaritsidny means Special instructions: In operating time with medicine it is forbidden to smoke, drink and eat food Upon termination of work it is necessary to wash up hands warm water with Nes soap it is necessary to iron an animal and to admit it to small children within 24 hours after processing by medicine At accidental hit of medicine on skin or mucous membranes it it is necessary to wash away immediately water During the work with Frontline of the Combo it is necessary to follow the rules of personal hygiene and safety measures provided for work with medicines for animals In operating time with medicine it is not allowed to drink, smoke, eat food At accidental hit Frontline of the Combo on skin or mucous membranes it should be washed away a water jet Upon termination of work of a hand it is necessary to wash up warm water with Pustyes soap pipettes from under medicine it is forbidden to use for the household purposes, they are subject to utilization with household waste Frontline of the Combo it is necessary to store in the place, inaccessible for children, date editing the description: 17.09.2021