tablets "Fiziotenz" apply in arterial hypertension.

Structure

Active ingredient: moksonidin.

1 tablet supports a moksonidin of 0.2 mg or 0.3 mg, or 0.4 mg.

Excipients: lactose monohydrate, K25 povidone; krospovidon; magnesium stearate.

a tablet: hipromeloza, ethyl celluloses water dispersion of 30%, macrogoal 6000, talc, ferrous oxide red (E172), titan dioxide (E 171).

Moksonidin is contraindicated to

Contraindication

• hypersensitivity to active ingredient or to any component of drug;
• sick sinus syndrome;
• bradycardia (ChSS at rest lower than 50 ud. / mines);
• to AV-blockade of II and III degree;
• heart failure.

Route of administration

Standard initial dose of a moksonidin makes 0.2 mg a day. The maximum single dose - 0.4 mg. The maximum daily dose - 0.6 mg - is applied in 2 receptions. The dose should be selected individually, depending on reaction of the patient.

Moksonidin can be accepted irrespective of meal, washing down with a small amount of liquid.

Pregnant

Corresponding do not have

Feature

Moksonidin is not recommended by

for use to children and teenagers (up to 18 years) because of insufficiency of data on safety and efficiency of medicament for this group of patients.

Drivers

Research about influence of medicament on ability to run motor transport or other mechanisms.

Overdose

In some cases overdoses of a moksonidin, even in the dose of 19.6 mg taken for 1 time did not lead to a lethal outcome. Signs and symptoms of overdose vomiting, fatigue, pain in an upper part of a stomach include a headache, sedation, drowsiness, arterial hypotension, dizziness, an asthenia, bradycardia, dryness in a mouth. In case of heavy overdose the careful monitoring of emergence of disturbances of consciousness and respiratory depression is recommended.

At accidental reception by the two-year-old child of unknown quantity of a moksonidin (perhaps, 14 mg) observed sedation, a coma, arterial hypotension, a miosis and an asthma. Gastric lavage, glucose infusion, controlled ventilation of the lungs and an immobilization led to total disappearance of symptoms during 11:00.

Considering researches of use of high doses of medicament for animals, it is in addition possible to expect emergence of orthostatic dysregulation, temporary hypertensia, tachycardia and a hyperglycemia.

Side effects

from mentality: often - insomnia; infrequently - nervousness.

from nervous system: often - a headache, dizziness, drowsiness infrequently - a syncope.

from organs of hearing and a labyrinth: infrequently - a ring in ears.

from a cardiovascular system: infrequently - bradycardia, hypotension * (including orthostatic hypotension).

from digestive tract: often - dryness in a mouth; often - diarrhea, nausea, vomiting, dyspepsia.

from skin and hypodermic fabric: often - rash, an itching infrequently - a Quincke's disease.

from a musculoskeletal system and connective tissue: often - a dorsodynia infrequently - neck pain.

General disturbances: often - an asthenia; infrequently - hypostasis.

to Store

in original packing at a temperature not above 25 °C, out of children's reach.

Expiration date: 2 years.