Elidel - dermatological means for treatment of patients aged from 2 years with slight and moderate atopic dermatitis if treatment by local corticosteroids is undesirable or is impossible. It can be at:

• intolerance of local corticosteroids;
• insufficient effect of local corticosteroids;
• requirement of use on a face and a neck where prolonged periodic use of corticosteroids can be inappropriate.

Structure

• active ingredient: pimecrolimus;
10 mg of a pimekrolimus contain
• 1 g of cream;
• other components: sodium hydroxide, anhydrous citric acid, benzyl alcohol, sodium tsetostearilsulfat, mono - and diglycerides, cetyl alcohol, stearyl alcohol, propylene glycol, oleyl alcohol, triglycerides of an average chain, water purified.

Contraindication

Hypersensitivity to a pimekrolimus, other macrolactams or other components of drug.

Side reactions

Infection: contagious mollusk.

from the immune system: anaphylactic reactions, including severe forms.

Metabolism and feeding habits: not tolerance to alcohol (in most cases feeling of rushes of blood, rash, burning, an itching or turgidity arising right after consumption of alcoholic drinks).

from skin and hypodermic cellulose: skin infections (folliculitis), a furuncle, impetigo, herpes a simplex, the surrounding herpes, gerpesny dermatitis (herpetic eczema), papilloma of skin and aggravation of symptoms, allergic reactions, including rash, skin colors (hypopigmentation, a hyperpegmentation).

General disorders and local reactions: burning sensation in the site of application of cream, reaction in the site of application (irritation, an itching, an erythema, rash, pain, paresthesia, peeling, dryness, hypostasis).

Route of administration

Duration of treatment is established by the doctor depending on a stage and severity of a disease.

Elidel can be applied quickly to treatment of symptoms of atopic eczema and periodically for a long time to prevention of exacerbation of a disease.

at emergence of the first symptoms of atopic dermatitis. Elidel it is necessary to apply only on the sites affected with atopic dermatitis. Elidel it is necessary to apply during the shortest period during exacerbation of a disease. The patient or the person who looks after him have to stop Elidel's use at disappearance of symptoms. Treatment has to be periodic and short-term.

with a thin layer on affected areas 2 times a day.

periodic use of Elidel during the period up to 12 months.

If after 6 weeks does not observe improvement or the condition of the patient worsens, Elidel's use should be stopped. At the same time it is necessary to estimate repeatedly the diagnosis of atopic dermatitis and to think over further therapeutic actions.

Adult. It is necessary to apply a thin group of Elidel to the affected skin 2 times a day and easy movements completely to rub in skin. Each of affected areas should be processed Elidel before disappearance of symptoms of a disease then treatment needs to be stopped.

Elidel can be applied on all sites of skin, including the head, a face, a neck and intertriginozny sites (sites of inguinal folds and genitalias), except mucous membranes. Elidel it is not necessary to apply at places under hard bandages.

Feature of use

Use during pregnancy or feeding by a breast

Considering the minimum level of absorption of a pimekrolimus after topical administration of Elidel possible risk for the person consider insignificant. However Elidel it is not necessary to use during pregnancy.

with care to women who nurse.

Woman which nurse can be applied Elidel, however should not apply it on the site of a breast in order to avoid inadvertent hit of medicament in an oral cavity of babies.

Elidel's Use is not recommended to children up to 2 years by

.

Ability to influence speed of response at control of motor transport or other mechanisms

by

.

Overdose

Messages about cases of overdose of Elidel.

Possible interactions of Elidel with other medicines systematically were not estimated by

. Pimekrolimus is metabolized only by CYP 450 3A4. Considering the minimum level of absorption of drug, Elidel's interaction with the medicaments used systemically it is improbable.

These data indicate

what Elidel can be applied along with antibiotics, antihistamines and glucocorticoids (peroral, nasal or inhalation).

Should avoid excess radiation of skin ultraviolet rays (including use of sunbeds, therapy by the ultraviolet radiation of a range In and And yes PUVA therapy) during treatment by Elidel.

by

observed exceptional cases of reddening, rash, burning sensation, an itching or hypostasis right after alcohol intake at the patients applying cream with pimekrolimusy.

Storage conditions

to Store

out of children's reach at a temperature not over 25C, not to freeze. After opening of a tuba, medicament should be used within 12 months.