Diyenogest Alvogen's tablets are shown for treatment of endometriosis.

Structure

Acting substance: diyenogest;

1 tablet, coated, contains the diyenogest 2 mg;

Excipients: lactose monohydrate, starch corn, (K-30), starch sodium (type A), magnesium stearate;

Film cover Akwa Polish white 014.17MS, supporting a gipromelloz (E 464), hydroxypropyl cellulose (E 463), talc (E 553b), cottonseed oil confectionery, the titan dioxide (E 171).

Contraindication

Drug should not be used in the presence of any of following states or diseases. This information is partially obtained on the basis of use of other medicines containing only progestogen. If any of these states or diseases arises for the first time during use of medicine, administration of medicament should be stopped immediately.

• Venous thrombembolia in an active form.
• Arterial or cardiovascular diseases in the anamnesis (for example a myocardial infarction, cerebrovascular an event, coronary heart disease).
• Diabetes with defeat of vessels.
• Serious illness of a liver now or their existence in the anamnesis, so far indicators of function of a liver not to norm.
• Tumour of a liver in the anamnesis (benign or malignant).
• Or expected malignant tumors dependent on sex hormones.
• Vaginal bleeding of not clear etiology.
• Hypersensitivity to active ingredient or to any of medicine components.

Route of administration

For oral administration.

on 1 tablet daily without interruption in administration of medicament approximately at the same time, washing down with a small amount of liquid. A pill can be taken irrespective of meal.

should take the Pill regularly, irrespective of menstrual bleeding. As soon as tablets from one packing ended, to begin to take a pill from the following packing, without taking a break in use of medicine.

Pregnant

it is not recommended by

Feature of application

by

for application for children before menarche.

Drivers

does not influence.

Overdose

Research of acute toxicity, carried out with diyenogesty, did not point out risk of development of acute side reactions in case of inadvertent reception of several daily therapeutic doses. No specific antidotes exist. Use of 20-30 mg of the diyenogest to day (that is 10-15 times higher, than a dose in a medicine tablet) within more than 24 weeks were transferred very well.

Side effects

Increase in body weight, suppressed mood, a sleep disorder, nervousness, decrease in a libido, changes of mood, a headache, migraine, nausea, an abdominal pain, a meteorism, an abdominal distension, vomiting, an acne, an alopecia, a dorsodynia, discomfort in mammary glands, a cyst of ovaries, inflows, uterine / vaginal bleedings, asthenic states, irritability.

Interaction

Proceeding from these researches of inhibition in vitro, is improbable development of clinically significant interaction of medicine with metabolism of other medicinal substances with participation of enzymes of a system of P450 cytochrome.

Reception of gestagen can affect results of some laboratory researches, including biochemical parameters of function of a liver, thyroid gland, adrenal glands and kidneys, plasma concentration of proteins, for example, of fraction of lipids/lipoproteids, parameters of carbohydrate metabolism and parameters of coagulation. Changes usually do not overstep the bounds of normal values.

Storage conditions

does not demand special storage conditions.

out of children's reach.

Expiration date - 2 years.