Bronkho-Munal contains the lyophilized lysate of bacteria most often causing respiratory infections including Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, Klebsiella ozaenae, Staphylococcus aureus, Streptococcus viridans, Streptococcus pyogenes, Moraxella catarrhalis.

natural protective properties of an organism against respiratory infections, reducing the frequency, duration and weight of a course of infectious diseases of airways and also reduces the need for antibiotics.

Drug activates the cellular and humoral immune response of a mucous membrane of airways and other immunocompetent structures of an organism. It also stimulates nonspecific the immune response of an organism. In preclinical and clinical trials such effects of medicine on protective mechanisms of an organism were shown:

• alveolar macrophages who cosecrete cytokines, protect an organism from infections;
• is increased by quantity of population of CD4 of T lymphocytes;
• activates the peripheral mononuclear cells performing protective function;
• IgA on mucous membranes of airways and a digestive tract
increases concentration secretory
• stimulates formation of protective adhesive molecules;
• is reduced by the maintenance of IgE in blood plasma that can suppress development of reactions of hypersensitivity.

Structure

Active ingredients: 1 capsule contains 3.5 mg of the lyophilized lysate of bacteria of Haemophilus influenzae, Streptococcus (Diplococcus) pneumoniae, Klebsiella pneumoniae and ozaenae, Staphylococcus aureus, Streptococcus pyogenes and viridans, Moraxella (Branhamella/Neisseria) catarrhalis;

Excipients: propyl gallate, sodium a glutamate, attracts (E 421), magnesium stearate, starch corn;

Cover: indigotin (E 132), titan dioxide (E 171), gelatin.

to Apply

Indication

Contraindication

Hypersensitivity to active agent or any auxiliary the substances which are a part of medicine.

Route of administration and doses

Children from 6 months to 12 years.

Cycle of preventive treatment of recurrent respiratory infections: on 1 capsule a day on an empty stomach within 10 days in a row in a month, 3 months in a row.

Interval between courses has to make 20 days.

at a sharp phase of respiratory infections in combination with other methods of treatment.

Capsule can be opened. If it is difficult for child to swallow the capsule, its contents can be stirred in corresponding drinks (water, fruit juice, milk).

should take the Drug in the morning on an empty stomach.

If forgot to give to the child medicine, it is necessary to give their next morning.

Overdose

noted accurate clinical symptoms of overdose by medicine. About cases of overdose it was not reported. In case of overdose it is necessary to see a doctor.

Side reactions

By-effects about which it was reported, classified below according to MedDRA by the systems of bodies and frequency: very often (≥ 1/10), it is frequent (≥ 1/100 to <1/10), infrequent (from ≥ 1/1000 to <1/100), rare (from ≥ 1/10000 to <1/1000), rare (<1/10000), including isolated cases, frequency is unknown (it is impossible to estimate on the available data).

from the immune system: infrequently - reactions of hypersensitivity (erythematic rashes, generalized rash, an erythema, swelled, the century, a face edema, peripheral hypostasis, a swelling, a swelling of the person, an itch, a generalized itch, short wind swelled).

from nervous system: often - a headache.

from the respiratory system, bodies of a thorax and mediastinum: often - cough.

from digestive tract: often - diarrhea, an abdominal pain infrequently - nausea, vomiting.

from skin and hypodermic fabrics: often - rash, infrequently - a small tortoiseshell frequency is unknown - a Quincke's disease.

General violations: infrequently - increased fatigue; single - fever.

in case of long gastrointestinal or respiratory frustration treatment needs to be stopped. At skin reactions the treatment is also interrupted as these manifestations can carry the allergic nature.

Use during pregnancy or feeding by a breast

Drug is not used by

Feature of application

Patient which intend to become pregnant or became pregnant, have to inform on it the doctor.

therefore it is desirable to avoid use of medicine during pregnancy.

No researches at the women nursing were conducted. Therefore it is necessary to be careful during feeding a breast.

medicine Use is not recommended to children up to 6 months by

in connection with immaturity of their immune system. To children 12 years are more senior to apply Bronkho-munal®, capsules on 7 mg.

Ability to influence speed of response at control of motor transport or other mechanisms

does not affect ability to drive the car and to use mechanisms.

Interaction with other medicines and other types of interactions

Interaction with other medicines it is at the moment unknown.

to Store

at a temperature not above 25 °C in original packing for protection against moisture.

to Store

out of children's reach.

Expiration date - 5 years.