tablets Aziklar are shown at treatment of the infections caused by microorganisms, sensitive to a klaritromitsin:

• Upper respiratory tract infection, that is nasopharynx (tonsillitis, pharyngitis), and infections of adnexal bosoms of a nose.
• Lower respiratory tract infection (bronchitis, acute lung fever and primary atypical pneumonia).
• Infection of leather and soft tissues (impetigo, folliculitis, erizipeloid, furunculosis, contaminated wounds).
• Acute and persistent dontogenous infections.
• Disseminated or localized mikobakterialny infections caused by Mycobacterium avium or Mycobacterium intracellulare. The localized infections caused by Mycobacterium chelonae, Mycobacterium fortuitum or Mycobacterium kansasii.
Eradikation's
• H. pylori at patients with a duodenum ulcer at oppression of secretion of hydrochloric acid (the activity of a klaritromitsin against H. pylori at neutral pH is higher, than at acid pH).

Structure

Active ingredient: 1 tablet, coated, supports a klaritromitsin - 500 mg.

Excipients: lactose, starch corn, sodium of a kroskarmelloz, magnesium stearate, cellulose microcrystalline, talc, sodium lauryl sulfate, film covering (hydroksipropilmetiltsellyuloza, tartrazine (E 102), polyethyleneglycol).

Contraindication

• Hypersensitivity to a klaritromitsin or to any component of medicine, or others of makrolidny antibiotics.
• Hypopotassemia (prolongation of an interval of QT).
• Heavy liver failure and the accompanying renal failure.
• Simultaneous application of a klaritromitsin with ticagrelor or ranolaziny.

Route of administration

Pill should be taken entirely (not to crush, not to chew), washing down with liquid. Food practically does not influence medicine absorption, but can slow down this process slightly.

makes 250 mg of a klaritromitsin each 12 hours, at heavy infections it is possible to raise a dose to 500 mg each 12 hours.

Usually the course of treatment makes 6-14 days. Duration of treatment depends on a course of the disease and is defined by the doctor individually for each patient.

Safety of use of medicine during pregnancy and feeding by a breast is not established to

Feature of application

. On the basis of the results received in researches on mice, rats, rabbits and monkeys, the possibility of an adverse effect on development of an embryo and a fruit cannot be excluded. It is not necessary to use medicament during pregnancy without careful assessment of a ratio advantage / risk.

Klaritromitsin is allocated to

in breast milk.

Children

use Drug to children aged from 12 years. Use of tablets of a klaritromitsin to children up to 12 years was not studied. To children of this age use medicament in the form of suspension.

Drivers

Data on influence are absent. However before control of vehicles and other mechanisms it is necessary to consider possible emergence of side reactions from nervous system, such as spasms, dizziness, hallucinations, confusion of consciousness, disorientation.

Overdose

Symptoms. The overdose of a klaritromitsin can lead to emergence of symptoms from digestive tract. At one patient with bipolar psychosis in the anamnesis, accepted 8 grams of a klaritromitsin, violations of the mental status, paranoid behavior, a hypopotassemia and an anoxemia developed.

Treatment. The side reactions accompanying overdoses it is necessary to treat by means of immediate gastric lavage and symptomatic therapy. As well as in others of macroleads, it is improbable that the hemodialysis or peritoneal dialysis significantly changed the level of a klaritromitsin in blood serum.

Side effects

Frequent and widespread side reactions at treatment klaritromitsiny adults and children is the abdominal pain, diarrhea, nausea, vomiting and a food faddism. These side reactions are usually slightly expressed and will be coordinated with the known profile of safety of makrolidny antibiotics.

Use of the below-mentioned medicines is strictly contraindicated to

because of possible development of serious consequences of interaction.

• Tsizaprid
• Pimozidum
• Astemizol.
• Terfenadin.

by

provided Below medicines which influence on concentration of a klaritromitsin in blood is known or it is supposed therefore change of a dose of a klaritromitsin or application of alternative therapy can be required.

• Efavirents.
• Nevirapin.
• Rifampitsin.
• Rifabutin.
• Rifapentin.

Storage conditions

to Store

at a temperature not above 30 °C in original packing.

to Store

out of children's reach.

Expiration date - 3 years.