Powder is applied to oral suspension "Аугментин™ ES" at infections at children aged from 3 months which body weight does not exceed 40 kg caused or presumably caused penitsilinrezistentnima by Streptococcus pneumoniae strains:

• sharp average otitis;
• community-acquired pneumonia.

Structure

1 bottle contains powder for preparation of 100 ml of suspension of the following Ingredients: 5 ml of suspension contain (active ingredients) of amoxicillin (in the form of trihydrate amoxicillin) 600 mg of clavulanic acid (in the form of clavulanate potassium) 42.9 mg.

Excipients: silicon dioxide colloidal waterless, sodium carboxymethylcellulose 12, aspartame (E 951), xanthane gum, silicon dioxide, artificial strawberry fragrance.

Contraindication

• hypersensitivity to medicine components, to any antibacterial agents of group of penicillin;
• existence in the anamnesis of the heavy reactions of hypersensitivity (including an anaphylaxis) connected with application of others beta laktamnykh agents (including cephalosporins, karbapenem or monobaktam);
• existence in the anamnesis of jaundice or the dysfunction of a liver connected with use of amoxicillin/clavulanic acid.

Route of administration Dosage is expressed to

by

in terms of the content of amoxicillin/clavulanic acid, except for cases when the dosage is expressed in terms of a separate component.

When choosing a dosage of medicine for treatment of a separate infection should be considered:

• probable infestants and their possible sensitivity to antibacterial drugs;
• severity and localizations of an infection;
• age, body weight and renal function of the patient, as shown below.

Course of treatment should not exceed

14 days without its viewing.

Adults and children with body weight ≥ 40 kg

Experience of application of "Augmentin™", suspension, to adults and children with body weight ≥ 40 kg are absent therefore recommendations concerning dosing for these groups of patients are absent.

Children aged from 3 months with body weight <40 kg

Recommended dose of the medicine "Augmentin™" makes 90/6.4 mg/kg/days, in 2 receptions.

other amount of clavulanic acid (in the form of potassium salt), than any other form of Augmentin™suspension contains

"Augmentin™ ES". "Augmentin™ ES" contains 42.9 mg of clavulanic acid on 5 ml of suspension whereas Augmentin™suspension of 200 mg / 5 contains ml 28.5 mg of clavulanic acid on 5 ml, and suspension of 400 mg / 5 contains ml 57 mg of clavulanic acid on 5 ml. Therefore "Augmentin™ ES" cannot be replaced with any other form of Augmentin™suspension.

Way of use is intended to

"Augmentin™ ES" by

for oral administration.

should take the Drug at meal time to minimize potential gastrointestinal intolerance.

Instruction for suspension preparation. Before application to check integrity of a seal on a cover. To stir up a bottle to loosen powder. To add a necessary amount of water (as shown below), to turn and to shake up carefully. Other way: to fill a bottle with water it is slightly below than a mark in the label, to turn and to shake up carefully, then to fill a bottle with water to a mark, to turn and again carefully to shake up.

Dosage of 600 mg / 42.9 mg / 5 ml:

• water volume which needs to be added for dissolution - 90 ml;
• final volume dissolved oral suspension - 100 ml.

Before each application a bottle should be shaken up carefully.

Feature of application

Pregnant

Should avoid use of medicine during pregnancy, except for cases when the doctor considers necessary it.

Both active components of medicine are excreted by

in breast milk (there is no information concerning influence of clavulanic acid on the baby who is on breastfeeding). Respectively at the baby who is on breastfeeding the appearance of diarrhea and fungal infection of mucous membranes is possible therefore feeding by a breast should be stopped. It is necessary to take possibility of allergic reactions into account. Amoxicillin/clavulanic acid during feeding by a breast can be applied only when, according to the doctor, the advantage of application prevails over risk.

Drivers

were not carried out by

Research on ability of medicine to influence speed of response at control of motor transport and work with mechanisms. However emergence of undesirable effects (such as allergic reactions, dizziness, spasms) is possible which can affect ability to drive the car and to work with mechanisms.

Overdose

Symptoms

Can be observed by

symptoms characteristic of disorder of digestive tract and violation of balance of liquid and electrolytes. The crystalluria connected with intake of amoxicillin that in some cases led to development of a renal failure was observed.

At patients with a renal failure and at the patients accepting high doses of medicine the developing of spasms is possible

.

to

It was reported about amoxicillin precipitation in bladder catheters, mainly after introduction in high doses. It is necessary to check passability of catheters regularly.

Treatment

Disturbance from digestive tract can treat symptomatically, paying attention to balance of liquids/electrolytes. Amoxicillin/clavulanic acid can be removed from a blood-groove by means of a hemodialysis.

to

Side effects

by

it was Most often reported about such side reactions on medicine as diarrhea, nausea and vomiting.

Storage conditions

to Store

at a temperature not above 25 °C, out of children's reach.

Prepared suspension to store

in the fridge at a temperature from 2 °C to 8 °C and to use within 10 days. Not to freeze.

Expiration date - 2 years (the prepared suspension - 10 days).