Acyclovir is the antiviral medicine having high activity of in vitro against a virus of a herpes simplex of the I and II types. Toxic action concerning cages of an organism of the owner it is minimum. Getting to the cells infected with a herpes virus, acyclovir is phosphorylated with formation of active connection - acyclovir triphosphate. The first stage of this process depends on existence of a virusokodovanoa of a thymidinekinase. Triphosphate of acyclovir works as inhibitor and substrate for a virus DNA polymerase, preventing further synthesis of virus DNA, not influencing usual cellular processes.

Indications

Infection of lips and the persons called by a virus of a herpes simplex (Herpes labialis).

Contraindication

should not appoint medicine to patients with the known hypersensitivity to acyclovir, a valatsiklovira, propylene glycol or to any other components of medicine.

not to use Drug for treatment of eyes.

Cream to apply

Feature of application

only to treatment of herpes on lips and a face. It is not necessary to apply cream on mucous membranes of an oral cavity, an eye and not to apply it to treatment of genital herpes to avoid local irritation. It is necessary to avoid accidental hit of cream in eyes.

Patients suffering from especially heavy manifestations of Herpes labialis demand consultation of the doctor. The faces sore with herpes of lips, it is necessary to warn against contact transfer of a virus to other people, especially in the presence of open defeats.

Cream is not recommended to be applied the patient with an immunodeficiency. Such patients need consultation of the doctor on treatment of any infection.

Route of administration and doses Drug is intended to

by

only for external use.

Cream to apply to

with a thin layer on an affected area of skin by means of a cotton plug of 5 times a day approximately everyone 4:00, except for night time. It is necessary to apply cream not only on affected areas of skin, but also around defeats. If when putting cream not to use a cotton plug, it is necessary to clean carefully hands directly before application for prevention of additional infection of affected areas of skin by bacterial and/or virus agents.

Treatment lasts at least 4 days, but therapy should be selected individually and to continue before hardening of a surface of a vesicle or before full treatment. Duration of treatment should not exceed 10 days. If symptoms of a disease do not disappear after 10 days of treatment, the patient needs to see a doctor.

Note: cream should be applied to achievement of optimum effect at the first symptoms of a herpes infection (pricking, the naggers, feeling of tightness, reddening).

Can begin with

treatment and at late stages - a papule or a bubble. Acyclovir to stop antiviral therapy at formation of a crust on an affected area of skin.

by

Overdose

Cases of overdose it was not observed. As medicine is intended only for topical administration, development of symptoms of overdose is improbable.

in case of suspicion on overdose needs to ask for medical care.

Special instructions

Use during pregnancy or feeding by a breast

during pregnancy and feeding by a breast medicament is recommended to be used only when the advantage, according to the doctor, exceeds possible risk.

Children

aged up to 12 years is not enough

Data on safety of use of medicine for children therefore children are recommended to appoint aged from 12 years.

Ability to influence speed of response at control of motor transport or other mechanisms

do not have data on influence of medicine on ability to steer motor transport or other mechanisms.

Structure

active ingredient: acyclovir;

50 mg of acyclovir contain

1 g of cream;

Excipients: dimetikon, stearilmakrogolglitserida, cetyl alcohol, oil mineral, paraffin white soft, propylene glycol, water purified.

Storage conditions

does not demand special storage conditions. To store out of children's reach.

Expiration date - 5 years.

After opening of a tuba - no more than 1 year.

not to use

after expiry date.