Tablets "Arifon ^® retard" are applied in essential hypertensia at adults.

Structure

Active ingredient - indapamin (one tablet contains 1.5 mg of an indapamid).

Excipients: lactoses monohydrate, gipromelloza (E 464), povidone, silicon dioxide colloidal anhydrous (E 551), magnesium stearate (E 470 V), titan dioxide (E 171), glycerin (E 422), macrogoal 6000.

Contraindication

• hypersensitivity to active ingredient, other streptocides or to any excipients;
• heavy renal failure;
• hepatic encephalopathy or heavy abnormal liver function;
• hypopotassemia.

Route of administration

For oral administration.

Dosage - one tablet a day, it is desirable in the morning. It is necessary to swallow of a tablet entirely, without chewing, washing down with water.

to increase in antihypertensive effect, but the diuretic effect increases.

Feature of use

Pregnant women

Data on use of an indapamid to pregnant women are absent or are limited (less than 300 cases). During the III trimester of pregnancy the decrease in volume of the circulating blood of the pregnant woman and an uteroplacental krovenapolneniye can be a consequence of prolonged use of thiazide diuretics that can give fetoplacental ischemia and an arrest of development of a fruit. As a precautionary measure it is desirable to avoid use of an indapamid at pregnancy.

. Indapamid it is not necessary to apply during feeding by a breast.

Influence on fertility of the person it is not expected p.

Safety and efficiency of use of medicament are not established to children by

.

Drivers

Drug "Arifon ^® retard" does not affect vigilance. But in case of undesirable reactions, including the symptoms connected with a lowering of arterial pressure, especially in an initiation of treatment or at use in a combination with other antihypertensive drug, ability to drive the car or work with other mechanisms it can be broken.

Overdose

Symptoms

overdose Symptoms first of all have manifestations of water and electrolytic disturbances (hyponatremia, a hypopotassemia). Developing of nausea, vomiting, arterial hypotension, spasm, drowsiness, dizziness (vertigo), confusion of consciousness, a polyuria or an oliguria to the anury (caused by a hypovolemia) is clinically possible.

Treatment

Measure of first aid include fast removal of medicament by gastric lavage and/or prescribing of activated carbon with the subsequent recovery of water and electrolytic balance in the conditions of a hospital.

Side effects

it was Most often reported about emergence of such side reactions: reactions of hypersensitivity, mainly dermatological, at the patients inclined to development of allergic and asthmatic reactions, and makulopapulezny rashes.

to Store

at a temperature not above 30 °C, out of children's reach.

Expiration date - 2 years.