Tablets Anaprilin-Zdorovye primernyatsya at the following indications. Control of essential and renal hypertensia, stenocardia, long preventive therapy after the postponed myocardial infarction, control of the majority of forms of arrhythmias of heart, prevention of migraine, an essential tremor, control of excitement and tachycardia of excitement, additional therapy in a thyrotoxicosis and thyrocardiac crisis; as a part of combination therapy - a pheochromocytoma (only in combination with α-adrenoceptors).

Structure

Active ingredient: 1 tablet contains propranolol of a hydrochloride 10 mg or 40 mg;

Excipients: talc, starch corn, gipromelloza, silicon dioxide colloidal, calcium stearate, cellulose microcrystalline.

Contraindication

Hypersensitivity to medicament components cardiogenic shock, AV blockade of II and III degree, sinuatrial blockade, a sick sinus syndrome, sinus bradycardia (heart rate less than 50 beats/min), Printsmetal's stenocardia, arterial hypotension, uncontrollable heart failure, bronchial asthma or a bronchospasm in the anamnesis, heavy disturbances of peripheric circulation, a metabolic acidosis (including diabetic acidosis), after long starvation, not treated pheochromocytoma, diabetes, chronic diseases of a liver.

Route of administration to Appoint

by

inside in 10-30 minutes prior to food, washing down with enough liquid. Dosing mode individual. The dose and duration of treatment are defined by the doctor.

to

Pregnant

to

Use during pregnancy is impossible for

Feature of use

except for cases when the expected therapeutic effect for the pregnant woman exceeds potential risk for a fruit.

Children Drug to appoint

by

to children aged from 3 years.

Drivers

With care.

Overdose

Symptoms: dizziness, profound arterial hypotension, bradycardia, arrhythmia, heart failure, collapse, Crocq's disease, spasms, breath difficulty, bronchospasm.

Treatment: gastric lavage, purpose of the adsorbing means.

Side effects

Drug is usually well transferred by

, but emergence of the following side reactions is possible.

• from heart: arterial hypotension, orthostatic hypotension, sinus bradycardia, blockade, development/progressing of heart failure, disturbances of peripheric circulation.
• from blood: thrombocytopenia, Werlhof's disease, leukopenia, agranulocytosis.
• from nervous system: asthenia, dizziness, headache, insomnia or drowsiness, nightmares, reduction of speed of mental and motor reactions, depression, concern, confusion of consciousness or short-term amnesia, paresthesias, hallucinations, spasms, psychoses, changes of mood.
• from an organ of sight: disturbance of visual acuity, reduction of secretion of plaintive liquid, dryness and morbidity of eyes, keratoconjunctivitis.
• from a respiratory system: pharyngitis, cough, short wind, respiratory distress syndrome, bronchial tube and laryngospasm.
• from digestive system: nausea, vomiting, pain in epigastric area, diarrhea or a constipation, thrombosis mezen arteries, ischemic colitis.
• from skin and hypodermic cellulose: skin reactions, itching, rash, alopecia, exacerbation of psoriasis, psoriazopodobny skin reactions.
• from an endocrine system: hypoglycemia.
• from vessels: a cold snap of extremities, exacerbation of the alternating lameness, Reynaud's syndrome.
• from digestive system: abnormal liver function (including cholestasia).

Interaction

Propranolol changes hypoglycemia tachycardia. To patients with diabetes, it is necessary to be careful at simultaneous use of propranolol and hypoglycemic means. Propranolol can prolong hypoglycemic reaction to insulin.

Antiarrhytmic medicaments of a class and Amiodaronum can strengthen influence of propranolol for the period of conductivity of auricles and cause negative inotropic effect.

Propranolol with extra care to apply

to patients who receive the accompanying treatment of a kardiodepresantama (chloroform, ether or related anesthetics), antiarrhytmic medicaments (quinidine, lidocaine, procaineamide) that aggravate depressive effects.

Guanetidin, reserpine, diuretics and other antihypertensive drugs, including medicaments of group of vazodilatator, can strengthen hypotensive effect of propranolol.

Storage conditions

to Store

in original packing at a temperature not above 25 °C.

to Store

out of children's reach.

Expiration date - 4 years.