Agerp cream of 5% of a tube of 2 g

Pharmacological properties

Agerp belongs to antiviral means which are highly effective concerning gerpesvirus, especially viruses of a herpes simplex of i and ii of type and also a virus of the surrounding herpes. after hit in the cell affected with a herpes virus, acyclovir turns into active triphosphate of acyclovir. its activity is connected with violation of synthesis of DNA of gerpesvirus in a cell of the person owing to oppression of function of a virus dnk-polymerase. acyclovir does not influence other cellular processes which are not connected with synthesis of virus DNA. the pharmacokinetics of medicine was not studied, but, considering these literatures, acyclovir in the form of cream has very low level of system absorption, even at repeated application.

Indication

Infection of lips and the persons called by a virus of a herpes simplex (herpes labialis).

Use

to Adults and children is aged more senior than 12 years cream agerp apply on affected areas of 5 times a day with an interval of 4 h, except for night time. it is important to begin treatment as soon as possible after emergence of the first symptoms of a disease. the minimum duration of treatment is 4 days if during this time there was no healing, treatment is continued up to 10 days. if within 10 days there did not occur recovery, it is necessary to see a doctor.

Contraindication

Hypersensitivity to acyclovir, other components of medicine or a valatsiklovir.

Drug in general is well transferred by

, but in certain cases can appear temporary sharp or a thermalgia in the place of application. insignificant drying and peeling of skin, an erythema and an itch can seldom be observed. development of contact dermatitis, and in some cases — a Quincke's disease after topical administration of cream with acyclovir is very seldom possible.

Special instructions

Cream agerp should be applied only at herpetic damages of a mucous membrane of lips and face skin. it is not recommended to apply medicine on mucous membranes of an oral cavity, eyes and genitals. in case of especially significant manifestations of a disease it is necessary to consult with the doctor. usually in the presence of herpetic defeats at persons with immunodeficiency appoint system treatment antiviral means therefore in such cases it is not necessary to apply independently without consultation of the doctor agerp.

Should avoid accidental hit of cream in eyes. In the presence of open damages of lips it must be kept in mind that the virus of a herpes simplex can be transmitted to other persons in the contact way.

Use during pregnancy and feeding by a breast. Agerp apply during pregnancy and feeding by a breast if the expected advantage for mother exceeds potential risk for a fruit or the child.

Children. Agerp at children aged up to 12 years because of the insufficient number of researches is not recommended to apply.

Ability to influence speed of response at control of vehicles or work with other mechanisms. Researches were not conducted.

Interaction

it is not revealed.

Overdose

These literatures demonstrate lack of any toxic influence at accidental topical or oral administration of all packing of medicine.

Storage conditions

At a temperature not higher than 25 s. not to freeze.